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Year Number of Results
2017 4
2018 52
2019 97
2020 117
2021 140
2022 93
2023 42
2024 36

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523 results

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The following term was not found in PubMed: RP220258
Page 1
ESR1 mutations in breast cancer.
Dustin D, Gu G, Fuqua SAW. Dustin D, et al. Cancer. 2019 Nov 1;125(21):3714-3728. doi: 10.1002/cncr.32345. Epub 2019 Jul 18. Cancer. 2019. PMID: 31318440 Free PMC article. Review.
The acquisition of ligand-independent ESR1 mutations during aromatase inhibitor therapy in metastatic estrogen receptor (ER)-positive breast cancer is a common mechanism of hormonal therapy resistance. Preclinical and clinical studies have demonstrated that ESR1 mutations …
The acquisition of ligand-independent ESR1 mutations during aromatase inhibitor therapy in metastatic estrogen receptor (ER)-positive breast …
Engineering the next generation of CAR-NK immunotherapies.
Biederstädt A, Rezvani K. Biederstädt A, et al. Int J Hematol. 2021 Nov;114(5):554-571. doi: 10.1007/s12185-021-03209-4. Epub 2021 Aug 28. Int J Hematol. 2021. PMID: 34453686 Free PMC article. Review.
Health Benefits of Coffee Consumption for Cancer and Other Diseases and Mechanisms of Action.
Safe S, Kothari J, Hailemariam A, Upadhyay S, Davidson LA, Chapkin RS. Safe S, et al. Int J Mol Sci. 2023 Jan 31;24(3):2706. doi: 10.3390/ijms24032706. Int J Mol Sci. 2023. PMID: 36769029 Free PMC article. Review.
In addition, there is also evidence that higher coffee consumption is associated with lower rates of colon and rectal cancer, as well as breast, endometrial, and other cancers, although for some of these cancers, the results are conflicting. ...Further elucid …
In addition, there is also evidence that higher coffee consumption is associated with lower rates of colon and rectal cancer, as well …
Mitochondria Targeting as an Effective Strategy for Cancer Therapy.
Ghosh P, Vidal C, Dey S, Zhang L. Ghosh P, et al. Int J Mol Sci. 2020 May 9;21(9):3363. doi: 10.3390/ijms21093363. Int J Mol Sci. 2020. PMID: 32397535 Free PMC article. Review.
Besides metabolic changes, mitochondrial dynamics such as fission and fusion are also altered in cancer cells. These alterations render mitochondria a vulnerable target for cancer therapy. ...It highlights novel approaches involving mitochondria targeting in canc …
Besides metabolic changes, mitochondrial dynamics such as fission and fusion are also altered in cancer cells. These alterations rend …
Integrated Metabolic Profiling and Transcriptional Analysis Reveals Therapeutic Modalities for Targeting Rapidly Proliferating Breast Cancers.
Liao C, Glodowski CR, Fan C, Liu J, Mott KR, Kaushik A, Vu H, Locasale JW, McBrayer SK, DeBerardinis RJ, Perou CM, Zhang Q. Liao C, et al. Cancer Res. 2022 Feb 15;82(4):665-680. doi: 10.1158/0008-5472.CAN-21-2745. Cancer Res. 2022. PMID: 34911787 Free PMC article.
Metabolic dysregulation is a prominent feature in breast cancer, but it remains poorly characterized in patient tumors. In this study, untargeted metabolomics analysis of triple-negative breast cancer (TNBC) and patient with estrogen receptor (ER)-positive breast …
Metabolic dysregulation is a prominent feature in breast cancer, but it remains poorly characterized in patient tumors. In this study …
Cancer-on-a-Chip: Models for Studying Metastasis.
Zhang X, Karim M, Hasan MM, Hooper J, Wahab R, Roy S, Al-Hilal TA. Zhang X, et al. Cancers (Basel). 2022 Jan 27;14(3):648. doi: 10.3390/cancers14030648. Cancers (Basel). 2022. PMID: 35158914 Free PMC article. Review.
The microfluidic-based cancer-on-a-chip models work as a powerful tool to study the tumor microenvironment and its role in metastasis. ...Finally, the popular design of microfluidic chip models for each step are discussed along with the challenges and perspectives of ca …
The microfluidic-based cancer-on-a-chip models work as a powerful tool to study the tumor microenvironment and its role in metastasis …
Regulation of aromatase in cancer.
Molehin D, Rasha F, Rahman RL, Pruitt K. Molehin D, et al. Mol Cell Biochem. 2021 Jun;476(6):2449-2464. doi: 10.1007/s11010-021-04099-0. Epub 2021 Feb 18. Mol Cell Biochem. 2021. PMID: 33599895 Review.
The regulation of aromatase, an enzyme involved in the biosynthesis of estrogen in normal and cancer cells, has been associated with growth factor signaling and immune response modulation. The tissue-specific regulatory roles of these factors are of particular importance a …
The regulation of aromatase, an enzyme involved in the biosynthesis of estrogen in normal and cancer cells, has been associated with …
The Role of DND1 in Cancers.
Zhang Y, Godavarthi JD, Williams-Villalobo A, Polk S, Matin A. Zhang Y, et al. Cancers (Basel). 2021 Jul 22;13(15):3679. doi: 10.3390/cancers13153679. Cancers (Basel). 2021. PMID: 34359581 Free PMC article. Review.
Although Dnd1(Ter) mutation causes spontaneous TGCT only in male 129 mice, it can also cause ovarian teratomas in mice when combined with other genetic defects or cause germ cell teratomas in both genders in the WKY/Ztm rat strain. Furthermore, studies on human cell lines, patien …
Although Dnd1(Ter) mutation causes spontaneous TGCT only in male 129 mice, it can also cause ovarian teratomas in mice when combined with ot …
The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer.
Kim J, Lee HM, Cai F, Ko B, Yang C, Lieu EL, Muhammad N, Rhyne S, Li K, Haloul M, Gu W, Faubert B, Kaushik AK, Cai L, Kasiri S, Marriam U, Nham K, Girard L, Wang H, Sun X, Kim J, Minna JD, Unsal-Kacmaz K, DeBerardinis RJ. Kim J, et al. Nat Metab. 2020 Dec;2(12):1401-1412. doi: 10.1038/s42255-020-00316-0. Epub 2020 Nov 30. Nat Metab. 2020. PMID: 33257855 Free PMC article.
In non-small-cell lung cancer (NSCLC), concurrent mutations in the oncogene KRAS and the tumour suppressor STK11 (also known as LKB1) encoding the kinase LKB1 result in aggressive tumours prone to metastasis but with liabilities arising from reprogrammed metabolism. We pre …
In non-small-cell lung cancer (NSCLC), concurrent mutations in the oncogene KRAS and the tumour suppressor STK11 (also known as LKB1) …
523 results