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Page 1
Key Targets and Molecular Mechanisms of Active Volatile Components of Rabdosia rubescens in Gastric Cancer Cells.
Hu Y, Cui Q, Ma D, Jin W, Li Y, Zhang J, Xu Y. Hu Y, et al. Curr Comput Aided Drug Des. 2022;18(7):493-505. doi: 10.2174/1573409918666221003091312. Curr Comput Aided Drug Des. 2022. PMID: 36200190 Free PMC article.
OBJECTIVE: To examine the effect and mechanism of volatile components of Rabdosia rubescens on gastric cancer. METHODS: Gas chromatography-mass spectrometry was used to detect and identify the volatile components of R. rubescens. ...The effects of vola …
OBJECTIVE: To examine the effect and mechanism of volatile components of Rabdosia rubescens on gastric cancer. METHODS: …
Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer.
Liu Y, Song Z, Liu Y, Ma X, Wang W, Ke Y, Xu Y, Yu D, Liu H. Liu Y, et al. Acta Pharm Sin B. 2021 Jun;11(6):1513-1525. doi: 10.1016/j.apsb.2021.05.006. Epub 2021 May 13. Acta Pharm Sin B. 2021. PMID: 34221865 Free PMC article.
Ferroptosis is a type of cell death accompanied by iron-dependent lipid peroxidation, thus stimulating ferroptosis may be a potential strategy for treating gastric cancer, therapeutic agents against which are urgently required. Jiyuan oridonin A (JDA) is a natural compound …
Ferroptosis is a type of cell death accompanied by iron-dependent lipid peroxidation, thus stimulating ferroptosis may be a potential strate …
Rabdosia rubescens inhibits breast cancer growth and angiogenesis.
Sartippour MR, Seeram NP, Heber D, Hardy M, Norris A, Lu Q, Zhang L, Lu M, Rao JY, Brooks MN. Sartippour MR, et al. Int J Oncol. 2005 Jan;26(1):121-7. Int J Oncol. 2005. PMID: 15586232
In mouse experiments, the extract from Rabdosia rubescens suppressed breast cancer xenograft size and decreased the tumor vessel density. We conclude that Rabdosia rubescens may potentially be used to treat or prevent breast cancer, and t …
In mouse experiments, the extract from Rabdosia rubescens suppressed breast cancer xenograft size and decreased the tum …
Cytotoxic ent-Kaurane Diterpenoids from Rabdosia Rubescens.
Wei WJ, Zhu B, Si Y, Guo T, Kang J, Dai L. Wei WJ, et al. Chem Biodivers. 2022 Oct;19(10):e202200497. doi: 10.1002/cbdv.202200497. Epub 2022 Sep 23. Chem Biodivers. 2022. PMID: 36050280
One new (1) and 11 reported ent-kaurane diterpenoids (2-12) were received from the ethanol extract of the air-dried aerial parts of Rabdosia rubescens collected in Jiyuan. Their structures were determined in accordance with high resolution electrospray ionization ma …
One new (1) and 11 reported ent-kaurane diterpenoids (2-12) were received from the ethanol extract of the air-dried aerial parts of Rabdo …
Network Pharmacology Research and Dual-omic Analyses Reveal the Molecular Mechanism of Natural Product Nodosin Inhibiting Muscle-Invasive Bladder Cancer in Vitro and in Vivo.
Hao X, Fan H, Yang J, Tang J, Zhou J, Zhao Y, Huang L, Xia Y. Hao X, et al. J Nat Prod. 2022 Aug 26;85(8):2006-2017. doi: 10.1021/acs.jnatprod.2c00400. Epub 2022 Aug 17. J Nat Prod. 2022. PMID: 35976233 Review.
Bladder cancer, specifically, muscle-invasive bladder cancer (MIBC), is among the most common malignant tumors. ...Nodosin, found in Isodon serra (Maxim.) Kudo (known as Xihuangcao), may inhibit bladder cancer cells. ...
Bladder cancer, specifically, muscle-invasive bladder cancer (MIBC), is among the most common malignant tumors. ...Nodosin, fo …
Rabdosia rubescens Linn: green synthesis of gold nanoparticles and their anticancer effects against human lung cancer cells A549.
Zhang X, Tan Z, Jia K, Zhang W, Dang M. Zhang X, et al. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):2171-2178. doi: 10.1080/21691401.2019.1620249. Artif Cells Nanomed Biotechnol. 2019. PMID: 31159596
Green synthesized nanoparticles are documented to possess a potent anticancer effect. Rabdosia rubescens is a Chinese plant which is also one of the components of PC-SPES and used to treat prostate cancer. ...Since lung cancer is reported to be with in …
Green synthesized nanoparticles are documented to possess a potent anticancer effect. Rabdosia rubescens is a Chinese plant wh …
Ent-kaurane diterpenoids from Rabdosia rubescens and their cytotoxic effects on human cancer cell lines.
Bai N, He K, Zhou Z, Tsai ML, Zhang L, Quan Z, Shao X, Pan MH, Ho CT. Bai N, et al. Planta Med. 2010 Feb;76(2):140-5. doi: 10.1055/s-0029-1186002. Epub 2009 Aug 3. Planta Med. 2010. PMID: 19653147
Two new ent-kaurane diterpenoids, 16,17-exo-epoxide-oridonin ( 1) and 11,15- O,O-diacetyl-rabdoternins D ( 2), together with thirteen known ones, were isolated from the aerial parts of Rabdosia rubescens. Their structures were established on the basis of high-field …
Two new ent-kaurane diterpenoids, 16,17-exo-epoxide-oridonin ( 1) and 11,15- O,O-diacetyl-rabdoternins D ( 2), together with thirteen known …
Jaridon 6, a new diterpene from Rabdosia rubescens (Hemsl.) Hara, can display anti-gastric cancer resistance by inhibiting SIRT1 and inducing autophagy.
Fu L, Han BK, Meng FF, Wang JW, Wang TY, Li HJ, Sun YY, Zou GN, Li XR, Li W, Bi YF, Ke Y, Liu HM. Fu L, et al. Phytother Res. 2021 Oct;35(10):5720-5733. doi: 10.1002/ptr.7231. Epub 2021 Aug 19. Phytother Res. 2021. PMID: 34411362
Tumor resistance is the main cause of treatment failure and is associated with many tumor factors. Jaridon 6, a new diterpene extracted from Rabdosia rubescens (Hemsl.) Hara, which has been previously extracted by our research team, has been tested having more obvio …
Tumor resistance is the main cause of treatment failure and is associated with many tumor factors. Jaridon 6, a new diterpene extracted from …
Inhibition of caspase-9 by oridonin, a diterpenoid isolated from Rabdosia rubescens, augments apoptosis in human laryngeal cancer cells.
Kang N, Cao SJ, Zhou Y, He H, Tashiro S, Onodera S, Qiu F, Ikejima T. Kang N, et al. Int J Oncol. 2015 Dec;47(6):2045-56. doi: 10.3892/ijo.2015.3186. Epub 2015 Sep 28. Int J Oncol. 2015. PMID: 26648189 Free PMC article.
Rabdosia rubescens, a commonly used traditional Chinese medicine, has increasingly gained attention for its use as an antitumor herb. Oridonin, a bioactive diterpenoid isolated from Rabdosia rubescens, has been reported to induce apoptosis in human lar …
Rabdosia rubescens, a commonly used traditional Chinese medicine, has increasingly gained attention for its use as an antitumo …
Reversal effects of Rabdosia rubescens extract on multidrug resistance of MCF-7/Adr cells in vitro.
Li F, Fan J, Wu Z, Liu RY, Guo L, Dong Z, Wang Z. Li F, et al. Pharm Biol. 2013 Sep;51(9):1196-203. doi: 10.3109/13880209.2013.784342. Epub 2013 Jun 19. Pharm Biol. 2013. PMID: 23777360
CONTEXT: Rabdosia rubescens (Hemsl.) Hara (Lamiaceae) is widely used in traditional Chinese medicines for the treatment of antitumor, antimicrobial, anti-inflammatory and antioxidation. ...OBJECTIVE: To investigate the multidrug resistance (MDR) reversal effects and …
CONTEXT: Rabdosia rubescens (Hemsl.) Hara (Lamiaceae) is widely used in traditional Chinese medicines for the treatment of ant …
271 results