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Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis.
Christoffolete MA, Linardi CC, de Jesus L, Ebina KN, Carvalho SD, Ribeiro MO, Rabelo R, Curcio C, Martins L, Kimura ET, Bianco AC. Christoffolete MA, et al. Among authors: rabelo r. Diabetes. 2004 Mar;53(3):577-84. doi: 10.2337/diabetes.53.3.577. Diabetes. 2004. PMID: 14988240
Regulation of the uncoupling protein gene expression.
Silva JE, Rabelo R. Silva JE, et al. Among authors: rabelo r. Eur J Endocrinol. 1997 Mar;136(3):251-64. doi: 10.1530/eje.0.1360251. Eur J Endocrinol. 1997. PMID: 9100546 Review.
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