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2013 2
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Page 1
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
Widjaja AA, Lim WW, Viswanathan S, Chothani S, Corden B, Dasan CM, Goh JWT, Lim R, Singh BK, Tan J, Pua CJ, Lim SY, Adami E, Schafer S, George BL, Sweeney M, Xie C, Tripathi M, Sims NA, Hübner N, Petretto E, Withers DJ, Ho L, Gil J, Carling D, Cook SA. Widjaja AA, et al. Among authors: lim r. Nature. 2024 Aug;632(8023):157-165. doi: 10.1038/s41586-024-07701-9. Epub 2024 Jul 17. Nature. 2024. PMID: 39020175 Free PMC article.
FOXO1 couples metabolic activity and growth state in the vascular endothelium.
Wilhelm K, Happel K, Eelen G, Schoors S, Oellerich MF, Lim R, Zimmermann B, Aspalter IM, Franco CA, Boettger T, Braun T, Fruttiger M, Rajewsky K, Keller C, Brüning JC, Gerhardt H, Carmeliet P, Potente M. Wilhelm K, et al. Among authors: lim r. Nature. 2016 Jan 14;529(7585):216-20. doi: 10.1038/nature16498. Epub 2016 Jan 6. Nature. 2016. PMID: 26735015 Free PMC article.
Top-NOTCH Regulation of Cardiac Metabolism.
Lim R, Potente M. Lim R, et al. Circulation. 2018 Jun 12;137(24):2609-2612. doi: 10.1161/CIRCULATIONAHA.118.033669. Circulation. 2018. PMID: 29891619 No abstract available.
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system.
Nadkarni R, Chu WC, Lee CQE, Mohamud Y, Yap L, Toh GA, Beh S, Lim R, Fan YM, Zhang YL, Robinson K, Tryggvason K, Luo H, Zhong F, Ho L. Nadkarni R, et al. Among authors: lim r. J Exp Med. 2022 Oct 3;219(10):e20212117. doi: 10.1084/jem.20212117. Epub 2022 Sep 21. J Exp Med. 2022. PMID: 36129453 Free PMC article.
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Serra H, Chivite I, Angulo-Urarte A, Soler A, Sutherland JD, Arruabarrena-Aristorena A, Ragab A, Lim R, Malumbres M, Fruttiger M, Potente M, Serrano M, Fabra À, Viñals F, Casanovas O, Pandolfi PP, Bigas A, Carracedo A, Gerhardt H, Graupera M. Serra H, et al. Among authors: lim r. Nat Commun. 2015 Jul 31;6:7935. doi: 10.1038/ncomms8935. Nat Commun. 2015. PMID: 26228240 Free PMC article.
Pid1 induces insulin resistance in both human and mouse skeletal muscle during obesity.
Bonala S, McFarlane C, Ang J, Lim R, Lee M, Chua H, Lokireddy S, Sreekanth P, Leow MK, Meng KC, Shyong TE, Lee YS, Gluckman PD, Sharma M, Kambadur R. Bonala S, et al. Among authors: lim r. Mol Endocrinol. 2013 Sep;27(9):1518-35. doi: 10.1210/me.2013-1048. Epub 2013 Aug 8. Mol Endocrinol. 2013. Retraction in: Mol Endocrinol. 2016 Aug;30(8):949. doi: 10.1210/me.2016-1094. PMID: 23927930 Free PMC article. Retracted.