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202 results
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The role of Notch in tumorigenesis: oncogene or tumour suppressor?
Radtke F, Raj K. Radtke F, et al. Nat Rev Cancer. 2003 Oct;3(10):756-67. doi: 10.1038/nrc1186. Nat Rev Cancer. 2003. PMID: 14570040 Review.
Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells.
Radtke F, Ferrero I, Wilson A, Lees R, Aguet M, MacDonald HR. Radtke F, et al. J Exp Med. 2000 Apr 3;191(7):1085-94. doi: 10.1084/jem.191.7.1085. J Exp Med. 2000. PMID: 10748227 Free PMC article.
Cutting edge: an essential role for Notch-1 in the development of both thymus-independent and -dependent T cells in the gut.
Wilson A, Ferrero I, MacDonald HR, Radtke F. Wilson A, et al. Among authors: radtke f. J Immunol. 2000 Nov 15;165(10):5397-400. doi: 10.4049/jimmunol.165.10.5397. J Immunol. 2000. PMID: 11067889
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.
Wolfer A, Bakker T, Wilson A, Nicolas M, Ioannidis V, Littman DR, Lee PP, Wilson CB, Held W, MacDonald HR, Radtke F. Wolfer A, et al. Among authors: radtke f. Nat Immunol. 2001 Mar;2(3):235-41. doi: 10.1038/85294. Nat Immunol. 2001. PMID: 11224523
Notch1 and T-cell development: insights from conditional knockout mice.
MacDonald HR, Wilson A, Radtke F. MacDonald HR, et al. Among authors: radtke f. Trends Immunol. 2001 Mar;22(3):155-60. doi: 10.1016/s1471-4906(00)01828-7. Trends Immunol. 2001. PMID: 11286731 Review.
Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.
Wilson A, MacDonald HR, Radtke F. Wilson A, et al. Among authors: radtke f. J Exp Med. 2001 Oct 1;194(7):1003-12. doi: 10.1084/jem.194.7.1003. J Exp Med. 2001. PMID: 11581321 Free PMC article.
Notch1 is required for neuronal and glial differentiation in the cerebellum.
Lütolf S, Radtke F, Aguet M, Suter U, Taylor V. Lütolf S, et al. Among authors: radtke f. Development. 2002 Jan;129(2):373-85. Development. 2002. PMID: 11807030
Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.
Wolfer A, Wilson A, Nemir M, MacDonald HR, Radtke F. Wolfer A, et al. Among authors: radtke f. Immunity. 2002 Jun;16(6):869-79. doi: 10.1016/s1074-7613(02)00330-8. Immunity. 2002. PMID: 12121668
The role of Notch signaling during hematopoietic lineage commitment.
Radtke F, Wilson A, Ernst B, MacDonald HR. Radtke F, et al. Immunol Rev. 2002 Sep;187:65-74. doi: 10.1034/j.1600-065x.2002.18706.x. Immunol Rev. 2002. PMID: 12366683 Review.
Notch1 functions as a tumor suppressor in mouse skin.
Nicolas M, Wolfer A, Raj K, Kummer JA, Mill P, van Noort M, Hui CC, Clevers H, Dotto GP, Radtke F. Nicolas M, et al. Among authors: radtke f. Nat Genet. 2003 Mar;33(3):416-21. doi: 10.1038/ng1099. Epub 2003 Feb 18. Nat Genet. 2003. PMID: 12590261
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