Rafiqi FH - Search Results

1

Structural insights into the recognition of substrates and activators by the OSR1 kinase.

Villa F, Goebel J, Rafiqi FH, Deak M, Thastrup J, Alessi DR, van Aalten DM. Villa F, et al. Among authors: rafiqi fh. EMBO Rep. 2007 Sep;8(9):839-45. doi: 10.1038/sj.embor.7401048. Epub 2007 Aug 17. EMBO Rep. 2007. PMID: 17721439 Free PMC article.

2

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.

Vitari AC, Thastrup J, Rafiqi FH, Deak M, Morrice NA, Karlsson HK, Alessi DR. Vitari AC, et al. Among authors: rafiqi fh. Biochem J. 2006 Jul 1;397(1):223-31. doi: 10.1042/BJ20060220. Biochem J. 2006. PMID: 16669787 Free PMC article.

3

Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress.

Zagórska A, Pozo-Guisado E, Boudeau J, Vitari AC, Rafiqi FH, Thastrup J, Deak M, Campbell DG, Morrice NA, Prescott AR, Alessi DR. Zagórska A, et al. Among authors: rafiqi fh. J Cell Biol. 2007 Jan 1;176(1):89-100. doi: 10.1083/jcb.200605093. Epub 2006 Dec 26. J Cell Biol. 2007. PMID: 17190791 Free PMC article.

4

Role of the WNK-activated SPAK kinase in regulating blood pressure.

Rafiqi FH, Zuber AM, Glover M, Richardson C, Fleming S, Jovanović S, Jovanović A, O'Shaughnessy KM, Alessi DR. Rafiqi FH, et al. EMBO Mol Med. 2010 Feb;2(2):63-75. doi: 10.1002/emmm.200900058. EMBO Mol Med. 2010. PMID: 20091762 Free PMC article.

5

SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.

Thastrup JO, Rafiqi FH, Vitari AC, Pozo-Guisado E, Deak M, Mehellou Y, Alessi DR. Thastrup JO, et al. Among authors: rafiqi fh. Biochem J. 2012 Jan 1;441(1):325-37. doi: 10.1042/BJ20111879. Biochem J. 2012. PMID: 22032326 Free PMC article.

6

Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1.

Richardson C, Rafiqi FH, Karlsson HK, Moleleki N, Vandewalle A, Campbell DG, Morrice NA, Alessi DR. Richardson C, et al. Among authors: rafiqi fh. J Cell Sci. 2008 Mar 1;121(Pt 5):675-84. doi: 10.1242/jcs.025312. Epub 2008 Feb 12. J Cell Sci. 2008. PMID: 18270262

7

Phenotypes of pseudohypoaldosteronism type II caused by the WNK4 D561A missense mutation are dependent on the WNK-OSR1/SPAK kinase cascade.

Chiga M, Rafiqi FH, Alessi DR, Sohara E, Ohta A, Rai T, Sasaki S, Uchida S. Chiga M, et al. Among authors: rafiqi fh. J Cell Sci. 2011 May 1;124(Pt 9):1391-5. doi: 10.1242/jcs.084111. Epub 2011 Apr 12. J Cell Sci. 2011. PMID: 21486947

8

SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2.

Reiche J, Theilig F, Rafiqi FH, Carlo AS, Militz D, Mutig K, Todiras M, Christensen EI, Ellison DH, Bader M, Nykjaer A, Bachmann S, Alessi D, Willnow TE. Reiche J, et al. Among authors: rafiqi fh. Mol Cell Biol. 2010 Jun;30(12):3027-37. doi: 10.1128/MCB.01560-09. Epub 2010 Apr 12. Mol Cell Biol. 2010. PMID: 20385770 Free PMC article.

9

Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway.

San-Cristobal P, Pacheco-Alvarez D, Richardson C, Ring AM, Vazquez N, Rafiqi FH, Chari D, Kahle KT, Leng Q, Bobadilla NA, Hebert SC, Alessi DR, Lifton RP, Gamba G. San-Cristobal P, et al. Among authors: rafiqi fh. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4384-9. doi: 10.1073/pnas.0813238106. Epub 2009 Feb 24. Proc Natl Acad Sci U S A. 2009. PMID: 19240212 Free PMC article.

10

PDCD4 Is an Androgen-Repressed Tumor Suppressor that Regulates Prostate Cancer Growth and Castration Resistance.

Zennami K, Choi SM, Liao R, Li Y, Dinalankara W, Marchionni L, Rafiqi FH, Kurozumi A, Hatano K, Lupold SE. Zennami K, et al. Among authors: rafiqi fh. Mol Cancer Res. 2019 Feb;17(2):618-627. doi: 10.1158/1541-7786.MCR-18-0837. Epub 2018 Dec 5. Mol Cancer Res. 2019. PMID: 30518628 Free PMC article.

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