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Angiotensin II (ATII)-inducible platelet-derived growth factor A-chain gene expression is p42/44 extracellular signal-regulated kinase-1/2 and Egr-1-dependent and mediated via the ATII type 1 but not type 2 receptor. Induction by ATII antagonized by nitric oxide.
Day FL, Rafty LA, Chesterman CN, Khachigian LM. Day FL, et al. Among authors: rafty la. J Biol Chem. 1999 Aug 20;274(34):23726-33. doi: 10.1074/jbc.274.34.23726. J Biol Chem. 1999. PMID: 10446131 Free article.
Metabolite of SIR2 reaction modulates TRPM2 ion channel.
Grubisha O, Rafty LA, Takanishi CL, Xu X, Tong L, Perraud AL, Scharenberg AM, Denu JM. Grubisha O, et al. Among authors: rafty la. J Biol Chem. 2006 May 19;281(20):14057-65. doi: 10.1074/jbc.M513741200. Epub 2006 Mar 24. J Biol Chem. 2006. PMID: 16565078 Free article.