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Prognostic value of coronary artery calcium screening in subjects with and without diabetes.
Raggi P, Shaw LJ, Berman DS, Callister TQ. Raggi P, et al. J Am Coll Cardiol. 2004 May 5;43(9):1663-9. doi: 10.1016/j.jacc.2003.09.068. J Am Coll Cardiol. 2004. PMID: 15120828

RESULTS: Patients with diabetes had a higher prevalence of hypertension and smoking (p < 0.001) and were older. The average coronary calcium score (CCS) for subjects with and for those without diabetes was 281 +/- 567 and 119 +/- 341, respectively (p < 0.0001)

RESULTS: Patients with diabetes had a higher prevalence of hypertension and smoking (p < 0.001) and were older. The average corona

Hemodynamic, catecholamine, vasomotor and vascular responses: Determinants of myocardial ischemia during mental stress.
Hammadah M, Alkhoder A, Al Mheid I, Wilmot K, Isakadze N, Abdulhadi N, Chou D, Obideen M, O'Neal WT, Sullivan S, Tahhan AS, Kelli HM, Ramadan R, Pimple P, Sandesara P, Shah AJ, Ward L, Ko YA, Sun Y, Uphoff I, Pearce B, Garcia EV, Kutner M, Bremner JD, Esteves F, Sheps DS, Raggi P, Vaccarino V, Quyyumi AA. Hammadah M, et al. Int J Cardiol. 2017 Sep 15;243:47-53. doi: 10.1016/j.ijcard.2017.05.093. Epub 2017 May 25. Int J Cardiol. 2017. PMID: 28571621 Free PMC article.
In comparison to those with no MSIMI, patients with MSIMI had higher hemodynamic and digital vasoconstrictive responses (p<0.05 for both), but did not differ in epinephrine, endothelial or macrovascular responses. ...
In comparison to those with no MSIMI, patients with MSIMI had higher hemodynamic and digital vasoconstrictive responses (p<0.05 fo …
Effect of intensive versus moderate lipid-lowering therapy on epicardial adipose tissue in hyperlipidemic post-menopausal women: a substudy of the BELLES trial (Beyond Endorsed Lipid Lowering with EBT Scanning).
Alexopoulos N, Melek BH, Arepalli CD, Hartlage GR, Chen Z, Kim S, Stillman AE, Raggi P. Alexopoulos N, et al. J Am Coll Cardiol. 2013 May 14;61(19):1956-61. doi: 10.1016/j.jacc.2012.12.051. Epub 2013 Mar 14. J Am Coll Cardiol. 2013. PMID: 23500254 Clinical Trial.

At the end of follow-up, EAT regressed more in the atorvastatin than in the pravastatin group (median, -3.38% vs. -0.83%, p = 0.025). The EAT percent change from baseline was significant in the atorvastatin, but not the pravastatin group (p < 0.001 and p =

At the end of follow-up, EAT regressed more in the atorvastatin than in the pravastatin group (median, -3.38% vs. -0.83%, p = 0.025). …
Effect of intensive atorvastatin therapy on coronary atherosclerosis progression, composition, arterial remodeling, and microvascular function.
Eshtehardi P, McDaniel MC, Dhawan SS, Binongo JN, Krishnan SK, Golub L, Corban MT, Raggi P, Quyyumi AA, Samady H. Eshtehardi P, et al. J Invasive Cardiol. 2012 Oct;24(10):522-9. J Invasive Cardiol. 2012. PMID: 23043036 Clinical Trial.
There was a trend toward lower percent fibrous tissue (-3.47 ± 1.78%; P=.07) and percent fibro-fatty tissue (-2.52 ± 1.24%; P=.06) and increase in percent necrotic core (+2.74 ± 1.65%; P=.11) and percent dense calcium (+1.99 ± 0.81; P=.02), which trans …
There was a trend toward lower percent fibrous tissue (-3.47 ± 1.78%; P=.07) and percent fibro-fatty tissue (-2.52 ± 1.24%; P= …
Inflammation is related to coronary flow reserve detected by positron emission tomography in asymptomatic male twins.
Vaccarino V, Khan D, Votaw J, Faber T, Veledar E, Jones DP, Goldberg J, Raggi P, Quyyumi AA, Bremner JD. Vaccarino V, et al. J Am Coll Cardiol. 2011 Mar 15;57(11):1271-9. doi: 10.1016/j.jacc.2010.09.074. J Am Coll Cardiol. 2011. PMID: 21392641 Free PMC article. Clinical Trial.
RESULTS: In within-pair analyses, all biomarkers, except VCAM-1, were higher in twins with lower CFR than their brothers with higher CFR (p < 0.05). ...
RESULTS: In within-pair analyses, all biomarkers, except VCAM-1, were higher in twins with lower CFR than their brothers with higher CFR ( …
The ADVANCE study: a randomized study to evaluate the effects of cinacalcet plus low-dose vitamin D on vascular calcification in patients on hemodialysis.
Raggi P, Chertow GM, Torres PU, Csiky B, Naso A, Nossuli K, Moustafa M, Goodman WG, Lopez N, Downey G, Dehmel B, Floege J; ADVANCE Study Group. Raggi P, et al. Nephrol Dial Transplant. 2011 Apr;26(4):1327-39. doi: 10.1093/ndt/gfq725. Epub 2010 Dec 8. Nephrol Dial Transplant. 2011. PMID: 21148030 Clinical Trial.
RESULTS: Median (P10, P90) Agatston CAC scores increased 24% (-22%, 119%) in the cinacalcet group and 31% (-9%, 179%) in the flexible vitamin D group (P = 0.073). Corresponding changes in volume CAC scores were 22% (-12%, 105%) and 30% (-6%, 133%; P = 0.009). Increa …
RESULTS: Median (P10, P90) Agatston CAC scores increased 24% (-22%, 119%) in the cinacalcet group and 31% (-9%, 179%) in the flexible vitami …
Heritability of renal function and inflammatory markers in adult male twins.
Raggi P, Su S, Karohl C, Veledar E, Rojas-Campos E, Vaccarino V. Raggi P, et al. Am J Nephrol. 2010;32(4):317-23. doi: 10.1159/000319449. Epub 2010 Aug 17. Am J Nephrol. 2010. PMID: 20720405 Free PMC article.
RESULTS: The mean eGFR was 89 ± 13 ml/min/1.73 m² (range 35-146); eGFR, intracellular adhesion molecule (ICAM) and TNF-α receptor (TNF-αR) were moderately heritable (all ∼50%), while IL-6 receptor (IL-6R) and P-selectin were highly heritable (68 and 76%, respectively). IL- …
RESULTS: The mean eGFR was 89 ± 13 ml/min/1.73 m² (range 35-146); eGFR, intracellular adhesion molecule (ICAM) and TNF-α receptor (TNF-αR) w …
Prompt-gamma compensation in Rb-82 myocardial perfusion 3D PET/CT.
Esteves FP, Nye JA, Khan A, Folks RD, Halkar RK, Garcia EV, Schuster DM, Lerakis S, Raggi P, Votaw JR. Esteves FP, et al. J Nucl Cardiol. 2010 Apr;17(2):247-53. doi: 10.1007/s12350-009-9170-1. Epub 2009 Nov 24. J Nucl Cardiol. 2010. PMID: 19937169
Combined impact of age and estimated glomerular filtration rate on in-hospital mortality after percutaneous coronary intervention for acute myocardial infarction (from the American College of Cardiology National Cardiovascular Data Registry).
Cardarelli F, Bellasi A, Ou FS, Shaw LJ, Veledar E, Roe MT, Morris DC, Peterson ED, Klein LW, Raggi P. Cardarelli F, et al. Am J Cardiol. 2009 Mar 15;103(6):766-71. doi: 10.1016/j.amjcard.2008.11.033. Epub 2009 Jan 24. Am J Cardiol. 2009. PMID: 19268729
Younger patients had fewer co-morbidities, higher estimated GFR, less frequent multivessel disease, and lower unadjusted mortality rates than older patients (p <0.0001 for all comparisons). ...
Younger patients had fewer co-morbidities, higher estimated GFR, less frequent multivessel disease, and lower unadjusted mortality rates tha …
Diagnostic performance of fusion of myocardial perfusion imaging (MPI) and computed tomography coronary angiography.
Santana CA, Garcia EV, Faber TL, Sirineni GK, Esteves FP, Sanyal R, Halkar R, Ornelas M, Verdes L, Lerakis S, Ramos JJ, Aguadé-Bruix S, Cuéllar H, Candell-Riera J, Raggi P. Santana CA, et al. J Nucl Cardiol. 2009 Mar-Apr;16(2):201-11. doi: 10.1007/s12350-008-9019-z. Epub 2009 Jan 22. J Nucl Cardiol. 2009. PMID: 19156478 Free PMC article.
The fusion technique performed better than MPI and MPI and CTA side-by-side for the presence of CAD in any vessel (overall area under the curve (AUC) for fused images: 0.89; P = .005 vs MPI, P = .04 vs side-by-side MPI-CTA) and for localization of CAD to the left an …
The fusion technique performed better than MPI and MPI and CTA side-by-side for the presence of CAD in any vessel (overall area under the cu …
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