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Lipid signaling in Drosophila photoreceptors.
Raghu P, Yadav S, Mallampati NB. Raghu P, et al. Biochim Biophys Acta. 2012 Aug;1821(8):1154-65. doi: 10.1016/j.bbalip.2012.03.008. Epub 2012 Mar 29. Biochim Biophys Acta. 2012. PMID: 22487656 Review.
Sensory transduction in these cells involves a high rate of G-protein coupled phosphatidylinositol 4,5 bisphosphate [PI(4,5)P(2)] hydrolysis ending with the activation of ion channels that are members of the TRP superfamily. ...
Sensory transduction in these cells involves a high rate of G-protein coupled phosphatidylinositol 4,5 bisphosphate [PI(4,5)P(2)] hyd …
The inositol 1,4,5-triphosphate receptor expression in Drosophila suggests a role for IP3 signalling in muscle development and adult chemosensory functions.
Raghu P, Hasan G. Raghu P, et al. Dev Biol. 1995 Oct;171(2):564-77. doi: 10.1006/dbio.1995.1305. Dev Biol. 1995. PMID: 7556937
Development of a functional assay for Ca2+ release activity of IP3R and expression of an IP3R gene fragment in the baculovirus-insect cell system.
Raghu P, Habib S, Hasnain SE, Hasan G. Raghu P, et al. Gene. 1997 Apr 29;190(1):151-6. doi: 10.1016/s0378-1119(97)80001-7. Gene. 1997. PMID: 9185861
Normal phototransduction in Drosophila photoreceptors lacking an InsP(3) receptor gene.
Raghu P, Colley NJ, Webel R, James T, Hasan G, Danin M, Selinger Z, Hardie RC. Raghu P, et al. Mol Cell Neurosci. 2000 May;15(5):429-45. doi: 10.1006/mcne.2000.0846. Mol Cell Neurosci. 2000. PMID: 10833300
Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors.
Hardie RC, Raghu P, Moore S, Juusola M, Baines RA, Sweeney ST. Hardie RC, et al. Among authors: raghu p. Neuron. 2001 Apr;30(1):149-59. doi: 10.1016/s0896-6273(01)00269-0. Neuron. 2001. PMID: 11343651
In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1).
Hardie RC, Gu Y, Martin F, Sweeney ST, Raghu P. Hardie RC, et al. Among authors: raghu p. J Biol Chem. 2004 Nov 12;279(46):47773-82. doi: 10.1074/jbc.M407525200. Epub 2004 Sep 7. J Biol Chem. 2004. PMID: 15355960
Functional INAD complexes are required to mediate degeneration in photoreceptors of the Drosophila rdgA mutant.
Georgiev P, Garcia-Murillas I, Ulahannan D, Hardie RC, Raghu P. Georgiev P, et al. Among authors: raghu p. J Cell Sci. 2005 Apr 1;118(Pt 7):1373-84. doi: 10.1242/jcs.01712. Epub 2005 Mar 8. J Cell Sci. 2005. PMID: 15755798
lazaro encodes a lipid phosphate phosphohydrolase that regulates phosphatidylinositol turnover during Drosophila phototransduction.
Garcia-Murillas I, Pettitt T, Macdonald E, Okkenhaug H, Georgiev P, Trivedi D, Hassan B, Wakelam M, Raghu P. Garcia-Murillas I, et al. Among authors: raghu p. Neuron. 2006 Feb 16;49(4):533-46. doi: 10.1016/j.neuron.2006.02.001. Neuron. 2006. PMID: 16476663
Regulation of Drosophila TRPC channels by protein and lipid interactions.
Raghu P. Raghu P. Semin Cell Dev Biol. 2006 Dec;17(6):646-53. doi: 10.1016/j.semcdb.2006.11.008. Epub 2006 Dec 1. Semin Cell Dev Biol. 2006. PMID: 17210264 Review.
TRP and TRPL are activated by G-protein coupled PI(4,5)P(2) hydrolysis through a mechanism in which IP(3) receptor mediated calcium release seems dispensable. Recent analysis has provided compelling evidence that the accurate turnover of PI(4,5)P(2) generated lipid …
TRP and TRPL are activated by G-protein coupled PI(4,5)P(2) hydrolysis through a mechanism in which IP(3) receptor mediated calcium r …
Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels.
Raghu P, Coessens E, Manifava M, Georgiev P, Pettitt T, Wood E, Garcia-Murillas I, Okkenhaug H, Trivedi D, Zhang Q, Razzaq A, Zaid O, Wakelam M, O'Kane CJ, Ktistakis N. Raghu P, et al. J Cell Biol. 2009 Apr 6;185(1):129-45. doi: 10.1083/jcb.200807027. J Cell Biol. 2009. PMID: 19349583 Free PMC article.
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