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116 results
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Genomic responses in mouse models poorly mimic human inflammatory diseases.
Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. Seok J, et al. Among authors: Rahme LG. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12. doi: 10.1073/pnas.1222878110. Epub 2013 Feb 11. Proc Natl Acad Sci U S A. 2013. PMID: 23401516 Free PMC article. Clinical Trial.
Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression.
Apidianakis Y, Mindrinos MN, Xiao W, Lau GW, Baldini RL, Davis RW, Rahme LG. Apidianakis Y, et al. Among authors: Rahme LG. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2573-8. doi: 10.1073/pnas.0409588102. Epub 2005 Feb 4. Proc Natl Acad Sci U S A. 2005. PMID: 15695583 Free PMC article.
Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication.
Déziel E, Lépine F, Milot S, He J, Mindrinos MN, Tompkins RG, Rahme LG. Déziel E, et al. Among authors: Rahme LG. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1339-44. doi: 10.1073/pnas.0307694100. Epub 2004 Jan 22. Proc Natl Acad Sci U S A. 2004. PMID: 14739337 Free PMC article.
Burn injury causes mitochondrial dysfunction in skeletal muscle.
Padfield KE, Astrakas LG, Zhang Q, Gopalan S, Dai G, Mindrinos MN, Tompkins RG, Rahme LG, Tzika AA. Padfield KE, et al. Among authors: Rahme LG. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5368-73. doi: 10.1073/pnas.0501211102. Epub 2005 Apr 4. Proc Natl Acad Sci U S A. 2005. PMID: 15809440 Free PMC article.
Analysis of factorial time-course microarrays with application to a clinical study of burn injury.
Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH; Inflammation and Host Response to Injury Program, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG 2nd, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'Keefe G. Zhou B, et al. Among authors: Rahme L. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):9923-8. doi: 10.1073/pnas.1002757107. Epub 2010 May 17. Proc Natl Acad Sci U S A. 2010. PMID: 20479259 Free PMC article.
Application of genome-wide expression analysis to human health and disease.
Cobb JP, Mindrinos MN, Miller-Graziano C, Calvano SE, Baker HV, Xiao W, Laudanski K, Brownstein BH, Elson CM, Hayden DL, Herndon DN, Lowry SF, Maier RV, Schoenfeld DA, Moldawer LL, Davis RW, Tompkins RG, Baker HV, Bankey P, Billiar T, Brownstein BH, Calvano SE, Camp D, Chaudry I, Cobb JP, Davis RW, Elson CM, Freeman B, Gamelli R, Gibran N, Harbrecht B, Hayden DL, Heagy W, Heimbach D, Herndon DN, Horton J, Hunt J, Laudanski K, Lederer J, Lowry SF, Maier RV, Mannick J, McKinley B, Miller-Graziano C, Mindrinos MN, Minei J, Moldawer LL, Moore E, Moore F, Munford R, Nathens A, O'keefe G, Purdue G, Rahme L, Remick D, Sailors M, Schoenfeld DA, Shapiro M, Silver G, Smith R, Stephanopoulos G, Stormo G, Tompkins RG, Toner M, Warren S, West M, Wolfe S, Xiao W, Young V; Inflammation and Host Response to Injury Large-Scale Collaborative Research Program. Cobb JP, et al. Among authors: Rahme L. Version 2. Proc Natl Acad Sci U S A. 2005 Mar 29;102(13):4801-6. doi: 10.1073/pnas.0409768102. Epub 2005 Mar 21. Proc Natl Acad Sci U S A. 2005. PMID: 15781863 Free PMC article.
The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes.
He J, Baldini RL, Déziel E, Saucier M, Zhang Q, Liberati NT, Lee D, Urbach J, Goodman HM, Rahme LG. He J, et al. Among authors: Rahme LG. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2530-5. doi: 10.1073/pnas.0304622101. Proc Natl Acad Sci U S A. 2004. PMID: 14983043 Free PMC article.
Plants and animals share functionally common bacterial virulence factors.
Rahme LG, Ausubel FM, Cao H, Drenkard E, Goumnerov BC, Lau GW, Mahajan-Miklos S, Plotnikova J, Tan MW, Tsongalis J, Walendziewicz CL, Tompkins RG. Rahme LG, et al. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8815-21. doi: 10.1073/pnas.97.16.8815. Proc Natl Acad Sci U S A. 2000. PMID: 10922040 Free PMC article. Review.
A quorum sensing small volatile molecule promotes antibiotic tolerance in bacteria.
Que YA, Hazan R, Strobel B, Maura D, He J, Kesarwani M, Panopoulos P, Tsurumi A, Giddey M, Wilhelmy J, Mindrinos MN, Rahme LG. Que YA, et al. Among authors: Rahme LG. PLoS One. 2013 Dec 19;8(12):e80140. doi: 10.1371/journal.pone.0080140. eCollection 2013. PLoS One. 2013. PMID: 24367477 Free PMC article.
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