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Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons.
Gonatopoulos-Pournatzis T, Wu M, Braunschweig U, Roth J, Han H, Best AJ, Raj B, Aregger M, O'Hanlon D, Ellis JD, Calarco JA, Moffat J, Gingras AC, Blencowe BJ. Gonatopoulos-Pournatzis T, et al. Among authors: raj b. Mol Cell. 2018 Nov 1;72(3):510-524.e12. doi: 10.1016/j.molcel.2018.10.008. Mol Cell. 2018. PMID: 30388412 Free article.
A highly conserved program of neuronal microexons is misregulated in autistic brains.
Irimia M, Weatheritt RJ, Ellis JD, Parikshak NN, Gonatopoulos-Pournatzis T, Babor M, Quesnel-Vallières M, Tapial J, Raj B, O'Hanlon D, Barrios-Rodiles M, Sternberg MJ, Cordes SP, Roth FP, Wrana JL, Geschwind DH, Blencowe BJ. Irimia M, et al. Among authors: raj b. Cell. 2014 Dec 18;159(7):1511-23. doi: 10.1016/j.cell.2014.11.035. Cell. 2014. PMID: 25525873 Free PMC article.
284 results