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Antiproliferative activity of N6-isopentenyladenosine on MCF-7 breast cancer cells: cell cycle analysis and DNA-binding study.
Rajabi M, Signorelli P, Gorincioi E, Ghidoni R, Santaniello E. Rajabi M, et al. DNA Cell Biol. 2010 Nov;29(11):687-91. doi: 10.1089/dna.2010.1073. Epub 2010 Sep 6. DNA Cell Biol. 2010. PMID: 20818975
A binding constant K(iPA-DNA) = 4.4 × 10(3) M(-1) was calculated and this value, together with the shift of absorbance, suggests iPA-DNA interaction at DNA surface....
A binding constant K(iPA-DNA) = 4.4 × 10(3) M(-1) was calculated and this value, together with the shift of absorbance, suggests iPA- …
Antiproliferative activity of novel derivative of thiopyran on breast and colon cancer lines and DNA binding.
Rajabi M, Khalilzadeh MA, Mehrzad J. Rajabi M, et al. DNA Cell Biol. 2012 Jan;31(1):128-34. doi: 10.1089/dna.2011.1291. Epub 2011 Jun 28. DNA Cell Biol. 2012. PMID: 21711159
The effect of ligand complexation on DNA structure led to overall affinity constant of K(4-DNA)=9.8×10(4) M(-1)....
The effect of ligand complexation on DNA structure led to overall affinity constant of K(4-DNA)=9.8×10(4) M(-1)....
DNA adducts with antioxidant flavonoids: morin, apigenin, and naringin.
Nafisi S, Hashemi M, Rajabi M, Tajmir-Riahi HA. Nafisi S, et al. DNA Cell Biol. 2008 Aug;27(8):433-42. doi: 10.1089/dna.2008.0735. DNA Cell Biol. 2008. PMID: 18491957
Spectroscopic evidence shows both intercalation and external binding of flavonoids to DNA duplex with overall binding constants of K(morin) = 5.99 x 10(3) M(-1), K(apigenin) = 7.10 x 10(4) M(-1), and K(naringin) = 3.10 x 10(3) M(-1). ...
Spectroscopic evidence shows both intercalation and external binding of flavonoids to DNA duplex with overall binding constants of K(morin) …
Antiproliferative activity of novel thiopyran analogs on MCF-7 breast and HCT-15 colon cancer cells: synthesis, cytotoxicity, cell cycle analysis, and DNA-binding.
Tavakolinia F, Baghipour T, Hossaini Z, Zareyee D, Khalilzadeh MA, Rajabi M. Tavakolinia F, et al. Nucleic Acid Ther. 2012 Aug;22(4):265-70. doi: 10.1089/nat.2012.0346. Epub 2012 Aug 16. Nucleic Acid Ther. 2012. PMID: 22897207 Free PMC article.
The effect of ligand complexation on DNA structure led to overall affinity constants of K(4a)=3.5×10(4) M(-1), K(4b)=6.4×10(4) M(-1), K(4c)=3.2×10(4) M(-1), and K(4d)=2.4×10(4) M(-1). ...
The effect of ligand complexation on DNA structure led to overall affinity constants of K(4a)=3.5×10(4) M(-1), K(4b)=6.4×10(4) M
Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line.
Rajabi M, Gorincioi E, Santaniello E. Rajabi M, et al. Nucleosides Nucleotides Nucleic Acids. 2012;31(6):474-81. doi: 10.1080/15257770.2012.681825. Nucleosides Nucleotides Nucleic Acids. 2012. PMID: 22646087
The cell cycle analysis by flow cytometry showed that KR arrested cell cycle progression in the S Phase by blocking through G(2)/M and G(0)/G(1) phase in HCT-15 colon cells. ...
The cell cycle analysis by flow cytometry showed that KR arrested cell cycle progression in the S Phase by blocking through G(2)/M an …
Naphthalene-fused (α-alkoxycarbonyl)methylene-γ-butyrolactones: antiproliferative activity and binding to bovine serum albumin and DNA.
Rajabi M, Khalilzadeh MA, Tavakolinia F, Signorelli P, Ghidoni R, Santaniello E. Rajabi M, et al. DNA Cell Biol. 2012 May;31(5):783-9. doi: 10.1089/dna.2011.1433. Epub 2011 Nov 10. DNA Cell Biol. 2012. PMID: 22074127
The binding constant K of the complex between the naphthyl lactone with bovine serum albumin (8 × 10(3) M(-1)) suggests a minor change in protein folding. The K of the binding with DNA (1.06 × 10(4) M(-1)) suggests nonspecific electrostatic interactions with DNA and …
The binding constant K of the complex between the naphthyl lactone with bovine serum albumin (8 × 10(3) M(-1)) suggests a minor chang …
Antiproliferative activity and cell cycle analysis of 2-(3,5-dihydroxyphenyl)-6-hydroxybenzothiazole on MCF-7 breast and HCT-15 colon cancer cell lines.
Rajabi M, Minutolo F, Bertini S, Macchia M, Ghidoni R. Rajabi M, et al. DNA Cell Biol. 2011 Aug;30(8):617-21. doi: 10.1089/dna.2011.1220. Epub 2011 Mar 25. DNA Cell Biol. 2011. PMID: 21438664
Synthesis of a new class of furo[3,2-c]coumarins and its anticancer activity.
Rajabi M, Hossaini Z, Khalilzadeh MA, Datta S, Halder M, Mousa SA. Rajabi M, et al. J Photochem Photobiol B. 2015 Jul;148:66-72. doi: 10.1016/j.jphotobiol.2015.03.027. Epub 2015 Apr 3. J Photochem Photobiol B. 2015. PMID: 25889947
UV-Vis spectroscopy was used for DNA and BSA-binding affinity of the compounds 1b and 1d and gave overall affinity constants of K1b-DNA=8.1×10(3) M(-1), K1d-DNA=1.1×10(4) M(-1), K1b-BSA=5.1×10(4) M(-1), and K1d-BSA=7.6×10(4) M(-1). ...
UV-Vis spectroscopy was used for DNA and BSA-binding affinity of the compounds 1b and 1d and gave overall affinity constants of K1b-DNA=8.1× …
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