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Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational Switching of PAGE4 at the Systems Level.
Lin X, Kulkarni P, Bocci F, Schafer NP, Roy S, Tsai MY, He Y, Chen Y, Rajagopalan K, Mooney SM, Zeng Y, Weninger K, Grishaev A, Onuchic JN, Levine H, Wolynes PG, Salgia R, Rangarajan G, Uversky V, Orban J, Jolly MK. Lin X, et al. Among authors: rajagopalan k. Biomolecules. 2019 Feb 22;9(2):77. doi: 10.3390/biom9020077. Biomolecules. 2019. PMID: 30813315 Free PMC article.
Cancer/testis antigen PAGE4, a regulator of c-Jun transactivation, is phosphorylated by homeodomain-interacting protein kinase 1, a component of the stress-response pathway.
Mooney SM, Qiu R, Kim JJ, Sacho EJ, Rajagopalan K, Johng D, Shiraishi T, Kulkarni P, Weninger KR. Mooney SM, et al. Among authors: rajagopalan k. Biochemistry. 2014 Mar 18;53(10):1670-9. doi: 10.1021/bi500013w. Epub 2014 Mar 5. Biochemistry. 2014. PMID: 24559171 Free PMC article.
Interestingly, however, while our previous observations indicated that the wild-type nonphosphorylated PAGE4 protein interacted with c-Jun [Rajagopalan , K. et al. ( 2014 ) Biochim, Biophys. Acta 1842 , 154 -163], here we show that phosphorylation of PAGE4 weakens i …
Interestingly, however, while our previous observations indicated that the wild-type nonphosphorylated PAGE4 protein interacted with c-Jun [ …
Protein folding and the order/disorder paradox.
Kulkarni P, Rajagopalan K, Yeater D, Getzenberg RH. Kulkarni P, et al. Among authors: rajagopalan k. J Cell Biochem. 2011 Jul;112(7):1949-52. doi: 10.1002/jcb.23115. J Cell Biochem. 2011. PMID: 21445877 Free PMC article.
Cancer/testis antigens and urological malignancies.
Kulkarni P, Shiraishi T, Rajagopalan K, Kim R, Mooney SM, Getzenberg RH. Kulkarni P, et al. Among authors: rajagopalan k. Nat Rev Urol. 2012 Jun 19;9(7):386-96. doi: 10.1038/nrurol.2012.117. Nat Rev Urol. 2012. PMID: 22710665 Free PMC article. Review.
426 results