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Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists.
Nawrocki AR, Rajala MW, Tomas E, Pajvani UB, Saha AK, Trumbauer ME, Pang Z, Chen AS, Ruderman NB, Chen H, Rossetti L, Scherer PE. Nawrocki AR, et al. Among authors: rajala mw. J Biol Chem. 2006 Feb 3;281(5):2654-60. doi: 10.1074/jbc.M505311200. Epub 2005 Dec 2. J Biol Chem. 2006. PMID: 16326714 Free article.
Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention.
Wang ZV, Schraw TD, Kim JY, Khan T, Rajala MW, Follenzi A, Scherer PE. Wang ZV, et al. Among authors: rajala mw. Mol Cell Biol. 2007 May;27(10):3716-31. doi: 10.1128/MCB.00931-06. Epub 2007 Mar 12. Mol Cell Biol. 2007. PMID: 17353260 Free PMC article.
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.
Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B, Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, Scherer PE. Lin Y, et al. J Biol Chem. 2005 Feb 11;280(6):4617-26. doi: 10.1074/jbc.M411863200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15536073
Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting.
Rajala MW, Qi Y, Patel HR, Takahashi N, Banerjee R, Pajvani UB, Sinha MK, Gingerich RL, Scherer PE, Ahima RS. Rajala MW, et al. Diabetes. 2004 Jul;53(7):1671-9. doi: 10.2337/diabetes.53.7.1671. Diabetes. 2004. PMID: 15220189
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity.
Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, Obici S, Deshaies Y, Ludgate M, Rossetti L, Scherer PE. Combs TP, et al. Endocrinology. 2004 Jan;145(1):367-83. doi: 10.1210/en.2003-1068. Epub 2003 Oct 23. Endocrinology. 2004. PMID: 14576179
Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin.
Combs TP, Berg AH, Rajala MW, Klebanov S, Iyengar P, Jimenez-Chillaron JC, Patti ME, Klein SL, Weinstein RS, Scherer PE. Combs TP, et al. Diabetes. 2003 Feb;52(2):268-76. doi: 10.2337/diabetes.52.2.268. Diabetes. 2003. PMID: 12540596
Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity.
Pajvani UB, Du X, Combs TP, Berg AH, Rajala MW, Schulthess T, Engel J, Brownlee M, Scherer PE. Pajvani UB, et al. J Biol Chem. 2003 Mar 14;278(11):9073-85. doi: 10.1074/jbc.M207198200. Epub 2002 Dec 20. J Biol Chem. 2003. PMID: 12496257
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