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The transcellular spread of cytosolic amyloids, prions, and prionoids.
Aguzzi A, Rajendran L. Aguzzi A, et al. Neuron. 2009 Dec 24;64(6):783-90. doi: 10.1016/j.neuron.2009.12.016. Neuron. 2009. PMID: 20064386 Review.
TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss.
Paolicelli RC, Jawaid A, Henstridge CM, Valeri A, Merlini M, Robinson JL, Lee EB, Rose J, Appel S, Lee VM, Trojanowski JQ, Spires-Jones T, Schulz PE, Rajendran L. Paolicelli RC, et al. Neuron. 2017 Jul 19;95(2):297-308.e6. doi: 10.1016/j.neuron.2017.05.037. Epub 2017 Jun 29. Neuron. 2017. PMID: 28669544 Free PMC article.
Membrane trafficking pathways in Alzheimer's disease.
Rajendran L, Annaert W. Rajendran L, et al. Traffic. 2012 Jun;13(6):759-70. doi: 10.1111/j.1600-0854.2012.01332.x. Epub 2012 Feb 17. Traffic. 2012. PMID: 22269004 Review.
Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects.
Vassar R, Kuhn PH, Haass C, Kennedy ME, Rajendran L, Wong PC, Lichtenthaler SF. Vassar R, et al. J Neurochem. 2014 Jul;130(1):4-28. doi: 10.1111/jnc.12715. Epub 2014 Apr 19. J Neurochem. 2014. PMID: 24646365 Free PMC article. Review.
Retromers in Alzheimer's disease.
Siegenthaler BM, Rajendran L. Siegenthaler BM, et al. Neurodegener Dis. 2012;10(1-4):116-21. doi: 10.1159/000335910. Epub 2012 Mar 3. Neurodegener Dis. 2012. PMID: 22398391 Review.
Cellular basis of Alzheimer's disease.
Bali J, Halima SB, Felmy B, Goodger Z, Zurbriggen S, Rajendran L. Bali J, et al. Ann Indian Acad Neurol. 2010 Dec;13(Suppl 2):S89-93. doi: 10.4103/0972-2327.74251. Ann Indian Acad Neurol. 2010. PMID: 21369424 Free PMC article.
Subcellular targeting strategies for drug design and delivery.
Rajendran L, Knölker HJ, Simons K. Rajendran L, et al. Nat Rev Drug Discov. 2010 Jan;9(1):29-42. doi: 10.1038/nrd2897. Nat Rev Drug Discov. 2010. PMID: 20043027 Review.
The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.
Filipello F, Morini R, Corradini I, Zerbi V, Canzi A, Michalski B, Erreni M, Markicevic M, Starvaggi-Cucuzza C, Otero K, Piccio L, Cignarella F, Perrucci F, Tamborini M, Genua M, Rajendran L, Menna E, Vetrano S, Fahnestock M, Paolicelli RC, Matteoli M. Filipello F, et al. Immunity. 2018 May 15;48(5):979-991.e8. doi: 10.1016/j.immuni.2018.04.016. Epub 2018 May 8. Immunity. 2018. PMID: 29752066
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