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Interleukin-10-deficient mice develop chronic enterocolitis.
Kühn R, Löhler J, Rennick D, Rajewsky K, Müller W. Kühn R, et al. Cell. 1993 Oct 22;75(2):263-74. doi: 10.1016/0092-8674(93)80068-p. Cell. 1993. PMID: 8402911
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation.
Roers A, Siewe L, Strittmatter E, Deckert M, Schlüter D, Stenzel W, Gruber AD, Krieg T, Rajewsky K, Müller W. Roers A, et al. J Exp Med. 2004 Nov 15;200(10):1289-97. doi: 10.1084/jem.20041789. Epub 2004 Nov 8. J Exp Med. 2004. PMID: 15534372 Free PMC article.
DNA polymerase kappa deficiency does not affect somatic hypermutation in mice.
Schenten D, Gerlach VL, Guo C, Velasco-Miguel S, Hladik CL, White CL, Friedberg EC, Rajewsky K, Esposito G. Schenten D, et al. Eur J Immunol. 2002 Nov;32(11):3152-60. doi: 10.1002/1521-4141(200211)32:11<3152::AID-IMMU3152>3.0.CO;2-2. Eur J Immunol. 2002. PMID: 12555660
IkappaB kinase signaling is essential for maintenance of mature B cells.
Pasparakis M, Schmidt-Supprian M, Rajewsky K. Pasparakis M, et al. J Exp Med. 2002 Sep 16;196(6):743-52. doi: 10.1084/jem.20020907. J Exp Med. 2002. PMID: 12235208 Free PMC article.
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2.
Pasparakis M, Courtois G, Hafner M, Schmidt-Supprian M, Nenci A, Toksoy A, Krampert M, Goebeler M, Gillitzer R, Israel A, Krieg T, Rajewsky K, Haase I. Pasparakis M, et al. Nature. 2002 Jun 20;417(6891):861-6. doi: 10.1038/nature00820. Nature. 2002. PMID: 12075355
How alpha beta T cells deal with induced TCR alpha ablation.
Polic B, Kunkel D, Scheffold A, Rajewsky K. Polic B, et al. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8744-9. doi: 10.1073/pnas.141218898. Epub 2001 Jul 10. Proc Natl Acad Sci U S A. 2001. PMID: 11447257 Free PMC article.
Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development.
Küppers R, Rajewsky K, Zhao M, Simons G, Laumann R, Fischer R, Hansmann ML. Küppers R, et al. Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10962-6. doi: 10.1073/pnas.91.23.10962. Proc Natl Acad Sci U S A. 1994. PMID: 7971992 Free PMC article.
Somatic hypermutation in normal and transformed human B cells.
Klein U, Goossens T, Fischer M, Kanzler H, Braeuninger A, Rajewsky K, Küppers R. Klein U, et al. Immunol Rev. 1998 Apr;162:261-80. doi: 10.1111/j.1600-065x.1998.tb01447.x. Immunol Rev. 1998. PMID: 9602370 Review.
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