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Page 1
The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE. Esser N, et al. Among authors: raleigh dp. Diabetologia. 2024 Sep;67(9):1897-1911. doi: 10.1007/s00125-024-06161-0. Epub 2024 Sep 9. Diabetologia. 2024. PMID: 39245780 Free PMC article.
Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology.
Akter R, Cao P, Noor H, Ridgway Z, Tu LH, Wang H, Wong AG, Zhang X, Abedini A, Schmidt AM, Raleigh DP. Akter R, et al. Among authors: raleigh dp. J Diabetes Res. 2016;2016:2798269. doi: 10.1155/2016/2798269. Epub 2015 Nov 15. J Diabetes Res. 2016. PMID: 26649319 Free PMC article. Review.
Interspecies Variation Affects Islet Amyloid Polypeptide Membrane Binding.
Sanders HM, Chalyavi F, Fields CR, Kostelic MM, Li MH, Raleigh DP, Zanni MT, Marty MT. Sanders HM, et al. Among authors: raleigh dp. J Am Soc Mass Spectrom. 2023 Jun 7;34(6):986-990. doi: 10.1021/jasms.3c00005. Epub 2023 Apr 26. J Am Soc Mass Spectrom. 2023. PMID: 37126782 Free PMC article.
Tuning protein autoinhibition by domain destabilization.
Cho JH, Muralidharan V, Vila-Perello M, Raleigh DP, Muir TW, Palmer AG 3rd. Cho JH, et al. Among authors: raleigh dp. Nat Struct Mol Biol. 2011 May;18(5):550-5. doi: 10.1038/nsmb.2039. Epub 2011 May 1. Nat Struct Mol Biol. 2011. PMID: 21532593 Free PMC article.
190 results