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Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19.
Meckiff BJ, Ramírez-Suástegui C, Fajardo V, Chee SJ, Kusnadi A, Simon H, Eschweiler S, Grifoni A, Pelosi E, Weiskopf D, Sette A, Ay F, Seumois G, Ottensmeier CH, Vijayanand P. Meckiff BJ, et al. Cell. 2020 Nov 25;183(5):1340-1353.e16. doi: 10.1016/j.cell.2020.10.001. Epub 2020 Oct 5. Cell. 2020. PMID: 33096020 Free PMC article.
Single-cell transcriptomic analysis of SARS-CoV-2 reactive CD4 + T cells.
Meckiff BJ, Ramírez-Suástegui C, Fajardo V, Chee SJ, Kusnadi A, Simon H, Grifoni A, Pelosi E, Weiskopf D, Sette A, Ay F, Seumois G, Ottensmeier CH, Vijayanand P. Meckiff BJ, et al. bioRxiv [Preprint]. 2020 Jun 13:2020.06.12.148916. doi: 10.1101/2020.06.12.148916. bioRxiv. 2020. PMID: 32587963 Free PMC article. Updated. Preprint.
Single-Cell Transcriptomic Analysis of SARS-CoV-2 Reactive CD4 + T Cells.
Meckiff BJ, Ramírez-Suástegui C, Fajardo V, Chee SJ, Kusnadi A, Simon H, Grifoni A, Pelosi E, Weiskopf D, Sette A, Ay F, Seumois G, Ottensmeier CH, Vijayanand P. Meckiff BJ, et al. SSRN [Preprint]. 2020 Jul 7:3641939. doi: 10.2139/ssrn.3641939. SSRN. 2020. PMID: 32742242 Free PMC article. Updated. Preprint.
Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy.
Eschweiler S, Clarke J, Ramírez-Suástegui C, Panwar B, Madrigal A, Chee SJ, Karydis I, Woo E, Alzetani A, Elsheikh S, Hanley CJ, Thomas GJ, Friedmann PS, Sanchez-Elsner T, Ay F, Ottensmeier CH, Vijayanand P. Eschweiler S, et al. Among authors: ramirez suastegui c. Nat Immunol. 2021 Aug;22(8):1052-1063. doi: 10.1038/s41590-021-00958-6. Epub 2021 Jun 24. Nat Immunol. 2021. PMID: 34168370 Free PMC article.
Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type-dependent effects of disease-risk variants.
Schmiedel BJ, Gonzalez-Colin C, Fajardo V, Rocha J, Madrigal A, Ramírez-Suástegui C, Bhattacharyya S, Simon H, Greenbaum JA, Peters B, Seumois G, Ay F, Chandra V, Vijayanand P. Schmiedel BJ, et al. Among authors: ramirez suastegui c. Sci Immunol. 2022 Feb 25;7(68):eabm2508. doi: 10.1126/sciimmunol.abm2508. Epub 2022 Feb 25. Sci Immunol. 2022. PMID: 35213211 Free PMC article.
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs.
Eschweiler S, Ramírez-Suástegui C, Li Y, King E, Chudley L, Thomas J, Wood O, von Witzleben A, Jeffrey D, McCann K, Simon H, Mondal M, Wang A, Dicker M, Lopez-Guadamillas E, Chou TF, Dobbs NA, Essame L, Acton G, Kelly F, Halbert G, Sacco JJ, Schache AG, Shaw R, McCaul JA, Paterson C, Davies JH, Brennan PA, Singh RP, Loadman PM, Wilson W, Hackshaw A, Seumois G, Okkenhaug K, Thomas GJ, Jones TM, Ay F, Friberg G, Kronenberg M, Vanhaesebroeck B, Vijayanand P, Ottensmeier CH. Eschweiler S, et al. Among authors: ramirez suastegui c. Nature. 2022 May;605(7911):741-746. doi: 10.1038/s41586-022-04685-2. Epub 2022 May 4. Nature. 2022. PMID: 35508656 Free PMC article. Clinical Trial.
20 results