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DL-2-hydroxyisocaproic acid attenuates inflammatory responses in a murine Candida albicans biofilm model.
Nieminen MT, Hernandez M, Novak-Frazer L, Kuula H, Ramage G, Bowyer P, Warn P, Sorsa T, Rautemaa R. Nieminen MT, et al. Clin Vaccine Immunol. 2014 Sep;21(9):1240-5. doi: 10.1128/CVI.00339-14. Epub 2014 Jul 2. Clin Vaccine Immunol. 2014. PMID: 24990903 Free PMC article.
Biofilm formation is a risk factor for mortality in patients with Candida albicans bloodstream infection-Scotland, 2012-2013.
Rajendran R, Sherry L, Nile CJ, Sherriff A, Johnson EM, Hanson MF, Williams C, Munro CA, Jones BJ, Ramage G. Rajendran R, et al. Clin Microbiol Infect. 2016 Jan;22(1):87-93. doi: 10.1016/j.cmi.2015.09.018. Epub 2015 Sep 30. Clin Microbiol Infect. 2016. PMID: 26432192 Free PMC article.
Azole resistance of Aspergillus fumigatus biofilms is partly associated with efflux pump activity.
Rajendran R, Mowat E, McCulloch E, Lappin DF, Jones B, Lang S, Majithiya JB, Warn P, Williams C, Ramage G. Rajendran R, et al. Antimicrob Agents Chemother. 2011 May;55(5):2092-7. doi: 10.1128/AAC.01189-10. Epub 2011 Feb 14. Antimicrob Agents Chemother. 2011. PMID: 21321135 Free PMC article.
Repurposing Pilocarpine Hydrochloride for Treatment of Candida albicans Infections.
Nile C, Falleni M, Cirasola D, Alghamdi A, Anderson OF, Delaney C, Ramage G, Ottaviano E, Tosi D, Bulfamante G, Morace G, Borghi E. Nile C, et al. mSphere. 2019 Jan 23;4(1):e00689-18. doi: 10.1128/mSphere.00689-18. mSphere. 2019. PMID: 30674648 Free PMC article.
Pilocarpine hydrochloride protected G. mellonella larvae from C. albicans infection via inhibition of C. albicans filamentation and appropriate regulation of cellular immunity. However, scopolamine abrogated the capacity of pilocarpine hydrochloride to protect G. me …
Pilocarpine hydrochloride protected G. mellonella larvae from C. albicans infection via inhibition of C. albicans filamentation and a …
A novel antifungal is active against Candida albicans biofilms and inhibits mutagenic acetaldehyde production in vitro.
Nieminen MT, Novak-Frazer L, Rautemaa V, Rajendran R, Sorsa T, Ramage G, Bowyer P, Rautemaa R. Nieminen MT, et al. PLoS One. 2014 May 27;9(5):e97864. doi: 10.1371/journal.pone.0097864. eCollection 2014. PLoS One. 2014. PMID: 24867320 Free PMC article. Corrected and republished.
Candida biofilms: an update.
Ramage G, Saville SP, Thomas DP, López-Ribot JL. Ramage G, et al. Eukaryot Cell. 2005 Apr;4(4):633-8. doi: 10.1128/EC.4.4.633-638.2005. Eukaryot Cell. 2005. PMID: 15821123 Free PMC article. Review. No abstract available.
Integrating Candida albicans metabolism with biofilm heterogeneity by transcriptome mapping.
Rajendran R, May A, Sherry L, Kean R, Williams C, Jones BL, Burgess KV, Heringa J, Abeln S, Brandt BW, Munro CA, Ramage G. Rajendran R, et al. Sci Rep. 2016 Oct 21;6:35436. doi: 10.1038/srep35436. Sci Rep. 2016. PMID: 27765942 Free PMC article.
Antifungal treatment affects the laboratory diagnosis of invasive aspergillosis.
McCulloch E, Ramage G, Rajendran R, Lappin DF, Jones B, Warn P, Shrief R, Kirkpatrick WR, Patterson TF, Williams C. McCulloch E, et al. J Clin Pathol. 2012 Jan;65(1):83-6. doi: 10.1136/jcp.2011.090464. Epub 2011 Nov 2. J Clin Pathol. 2012. PMID: 22049217
RESULTS: No significant differences were observed in the CE/g of Aspergillus fumigatus in the lungs of each group. qPCR was statistically more sensitive than galactomannan for both the early detection of infected controls (p=0.045) and for overall detection (p=0.018). ...
RESULTS: No significant differences were observed in the CE/g of Aspergillus fumigatus in the lungs of each group. qPCR was statistic …
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