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Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes.
Petersen J, Wurzbacher SJ, Williamson NA, Ramarathinam SH, Reid HH, Nair AK, Zhao AY, Nastovska R, Rudge G, Rossjohn J, Purcell AW. Petersen J, et al. Among authors: ramarathinam sh. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2776-81. doi: 10.1073/pnas.0812901106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196958 Free PMC article.
An open-source computational and data resource to analyze digital maps of immunopeptidomes.
Caron E, Espona L, Kowalewski DJ, Schuster H, Ternette N, Alpízar A, Schittenhelm RB, Ramarathinam SH, Lindestam Arlehamn CS, Chiek Koh C, Gillet LC, Rabsteyn A, Navarro P, Kim S, Lam H, Sturm T, Marcilla M, Sette A, Campbell DS, Deutsch EW, Moritz RL, Purcell AW, Rammensee HG, Stevanovic S, Aebersold R. Caron E, et al. Among authors: ramarathinam sh. Elife. 2015 Jul 8;4:e07661. doi: 10.7554/eLife.07661. Elife. 2015. PMID: 26154972 Free PMC article.
MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Pymm P, Illing PT, Ramarathinam SH, O'Connor GM, Hughes VA, Hitchen C, Price DA, Ho BK, McVicar DW, Brooks AG, Purcell AW, Rossjohn J, Vivian JP. Pymm P, et al. Among authors: ramarathinam sh. Nat Struct Mol Biol. 2017 Apr;24(4):387-394. doi: 10.1038/nsmb.3381. Epub 2017 Feb 20. Nat Struct Mol Biol. 2017. PMID: 28218747 Free PMC article.
Spliced Peptides and Cytokine-Driven Changes in the Immunopeptidome of Melanoma.
Faridi P, Woods K, Ostrouska S, Deceneux C, Aranha R, Duscharla D, Wong SQ, Chen W, Ramarathinam SH, Lim Kam Sian TCC, Croft NP, Li C, Ayala R, Cebon JS, Purcell AW, Schittenhelm RB, Behren A. Faridi P, et al. Among authors: ramarathinam sh. Cancer Immunol Res. 2020 Oct;8(10):1322-1334. doi: 10.1158/2326-6066.CIR-19-0894. Epub 2020 Sep 16. Cancer Immunol Res. 2020. PMID: 32938616
46 results