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Rapid single-nucleotide polymorphism detection of cytochrome P450 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genes for the warfarin dose adjustment by the SMart-amplification process version 2.
Aomori T, Yamamoto K, Oguchi-Katayama A, Kawai Y, Ishidao T, Mitani Y, Kogo Y, Lezhava A, Fujita Y, Obayashi K, Nakamura K, Kohnke H, Wadelius M, Ekström L, Skogastierna C, Rane A, Kurabayashi M, Murakami M, Cizdziel PE, Hayashizaki Y, Horiuchi R. Aomori T, et al. Among authors: rane a. Clin Chem. 2009 Apr;55(4):804-12. doi: 10.1373/clinchem.2008.115295. Epub 2009 Jan 30. Clin Chem. 2009. PMID: 19181737
The largest prospective warfarin-treated cohort supports genetic forecasting.
Wadelius M, Chen LY, Lindh JD, Eriksson N, Ghori MJ, Bumpstead S, Holm L, McGinnis R, Rane A, Deloukas P. Wadelius M, et al. Among authors: rane a. Blood. 2009 Jan 22;113(4):784-92. doi: 10.1182/blood-2008-04-149070. Epub 2008 Jun 23. Blood. 2009. PMID: 18574025 Free PMC article.
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