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Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats.
Rubinsztein DC, Leggo J, Coles R, Almqvist E, Biancalana V, Cassiman JJ, Chotai K, Connarty M, Crauford D, Curtis A, Curtis D, Davidson MJ, Differ AM, Dode C, Dodge A, Frontali M, Ranen NG, Stine OC, Sherr M, Abbott MH, Franz ML, Graham CA, Harper PS, Hedreen JC, Hayden MR, et al. Rubinsztein DC, et al. Among authors: ranen ng. Am J Hum Genet. 1996 Jul;59(1):16-22. Am J Hum Genet. 1996. PMID: 8659522 Free PMC article.
cDNA cloning of a human homologue of the Caenorhabditis elegans cell fate-determining gene mab-21: expression, chromosomal localization and analysis of a highly polymorphic (CAG)n trinucleotide repeat.
Margolis RL, Stine OC, McInnis MG, Ranen NG, Rubinsztein DC, Leggo J, Brando LV, Kidwai AS, Loev SJ, Breschel TS, Callahan C, Simpson SG, DePaulo JR, McMahon FJ, Jain S, Paykel ES, Walsh C, DeLisi LE, Crow TJ, Torrey EF, Ashworth RG, Macke JP, Nathans J, Ross CA. Margolis RL, et al. Among authors: ranen ng. Hum Mol Genet. 1996 May;5(5):607-16. doi: 10.1093/hmg/5.5.607. Hum Mol Genet. 1996. PMID: 8733127
A controlled trial of idebenone in Huntington's disease.
Ranen NG, Peyser CE, Coyle JT, Bylsma FW, Sherr M, Day L, Folstein MF, Brandt J, Ross CA, Folstein SE. Ranen NG, et al. Mov Disord. 1996 Sep;11(5):549-54. doi: 10.1002/mds.870110510. Mov Disord. 1996. PMID: 8866496 Clinical Trial.
When does Huntington's disease begin?
Campodonico JR, Aylward E, Codori AM, Young C, Krafft L, Magdalinski M, Ranen N, Slavney PR, Brandt J. Campodonico JR, et al. J Int Neuropsychol Soc. 1998 Sep;4(5):467-73. doi: 10.1017/s1355617798455061. J Int Neuropsychol Soc. 1998. PMID: 9745236
16 results