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Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance.
Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2111451118. doi: 10.1073/pnas.2111451118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34750265
Free PMC article.
Resistance to kinase inhibition through shortened target engagement.
Rangwala AM, Berger BT, Robers MB, Knapp S, Seeliger MA.
Rangwala AM, et al.
Mol Cell Oncol. 2022 Jan 22;9(1):2029999. doi: 10.1080/23723556.2022.2029999. eCollection 2022.
Mol Cell Oncol. 2022.
PMID: 35252553
Free PMC article.
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Validation of an Allosteric Binding Site of Src Kinase Identified by Unbiased Ligand Binding Simulations.
Mingione VR, Foda ZH, Paung Y, Philipose H, Rangwala AM, Shan Y, Seeliger MA.
Mingione VR, et al. Among authors: rangwala am.
J Mol Biol. 2022 Sep 15;434(17):167628. doi: 10.1016/j.jmb.2022.167628. Epub 2022 May 17.
J Mol Biol. 2022.
PMID: 35595169
Free PMC article.
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Kinases on Double Duty: A Review of UniProtKB Annotated Bifunctionality within the Kinome.
Rangwala AM, Mingione VR, Georghiou G, Seeliger MA.
Rangwala AM, et al.
Biomolecules. 2022 May 11;12(5):685. doi: 10.3390/biom12050685.
Biomolecules. 2022.
PMID: 35625613
Free PMC article.
Review.
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Discovery and molecular basis of subtype-selective cyclophilin inhibitors.
Peterson AA, Rangwala AM, Thakur MK, Ward PS, Hung C, Outhwaite IR, Chan AI, Usanov DL, Mootha VK, Seeliger MA, Liu DR.
Peterson AA, et al. Among authors: rangwala am.
Nat Chem Biol. 2022 Nov;18(11):1184-1195. doi: 10.1038/s41589-022-01116-1. Epub 2022 Sep 26.
Nat Chem Biol. 2022.
PMID: 36163383
Free PMC article.
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