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Molecular mechanisms of glioma invasiveness: the role of proteases.
Rao JS. Rao JS. Nat Rev Cancer. 2003 Jul;3(7):489-501. doi: 10.1038/nrc1121. Nat Rev Cancer. 2003. PMID: 12835669 Review.
RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.
Kunigal S, Lakka SS, Gondi CS, Estes N, Rao JS. Kunigal S, et al. Among authors: rao js. Int J Cancer. 2007 Nov 15;121(10):2307-16. doi: 10.1002/ijc.22962. Int J Cancer. 2007. PMID: 17657740 Free PMC article.
Down-regulation of uPAR and uPA activates caspase-mediated apoptosis and inhibits the PI3K/AKT pathway.
Gondi CS, Kandhukuri N, Dinh DH, Gujrati M, Rao JS. Gondi CS, et al. Among authors: rao js. Int J Oncol. 2007 Jul;31(1):19-27. Int J Oncol. 2007. PMID: 17549401 Free PMC article.
RNA interference-mediated targeting of urokinase plasminogen activator receptor and matrix metalloproteinase-9 gene expression in the IOMM-lee malignant meningioma cell line inhibits tumor growth, tumor cell invasion and angiogenesis.
Tummalapalli P, Gondi CS, Dinh DH, Gujrati M, Rao JS. Tummalapalli P, et al. Among authors: rao js. Int J Oncol. 2007 Jul;31(1):5-17. Int J Oncol. 2007. PMID: 17549400 Free PMC article.
Sense p16 and antisense uPAR bicistronic construct inhibits angiogenesis and induces glioma cell death.
Nalabothula N, Lakka SS, Dinh DH, Gujrati M, Olivero WC, Rao JS. Nalabothula N, et al. Among authors: rao js. Int J Oncol. 2007 Mar;30(3):669-78. Int J Oncol. 2007. PMID: 17273768 Free PMC article.
RNA interference-mediated simultaneous down-regulation of urokinase-type plasminogen activator receptor and cathepsin B induces caspase-8-mediated apoptosis in SNB19 human glioma cells.
Gondi CS, Kandhukuri N, Kondraganti S, Gujrati M, Olivero WC, Dinh DH, Rao JS. Gondi CS, et al. Among authors: rao js. Mol Cancer Ther. 2006 Dec;5(12):3197-208. doi: 10.1158/1535-7163.MCT-05-0531. Mol Cancer Ther. 2006. PMID: 17172424 Free PMC article.
RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth.
Kondraganti S, Gondi CS, McCutcheon I, Dinh DH, Gujrati M, Rao JS, Olivero WC. Kondraganti S, et al. Among authors: rao js. Int J Oncol. 2006 Jun;28(6):1353-60. Int J Oncol. 2006. PMID: 16685436 Free PMC article.
siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells.
Subramanian R, Gondi CS, Lakka SS, Jutla A, Rao JS. Subramanian R, et al. Among authors: rao js. Int J Oncol. 2006 Apr;28(4):831-9. Int J Oncol. 2006. PMID: 16525631 Free PMC article.
Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells.
Rao JS, Gondi C, Chetty C, Chittivelu S, Joseph PA, Lakka SS. Rao JS, et al. Mol Cancer Ther. 2005 Sep;4(9):1399-408. doi: 10.1158/1535-7163.MCT-05-0082. Mol Cancer Ther. 2005. PMID: 16170032 Free PMC article.
Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas.
Lakka SS, Gondi CS, Dinh DH, Olivero WC, Gujrati M, Rao VH, Sioka C, Rao JS. Lakka SS, et al. Among authors: rao vh, rao js. J Biol Chem. 2005 Jun 10;280(23):21882-92. doi: 10.1074/jbc.M408520200. Epub 2005 Apr 11. J Biol Chem. 2005. PMID: 15824107 Retracted.
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