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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Harrison DE, et al. Nature. 2009 Jul 16;460(7253):392-5. doi: 10.1038/nature08221. Epub 2009 Jul 8. Nature. 2009. PMID: 19587680 Free PMC article.
Inhibition of the TOR signalling pathway by genetic or pharmacological intervention extends lifespan in invertebrates, including yeast, nematodes and fruitflies; however, whether inhibition of mTOR signalling can extend lifespan in a mammalian s …
Inhibition of the TOR signalling pathway by genetic or pharmacological intervention extends lifespan in invertebrates, …
Rapamycin extends life and health in C57BL/6 mice.
Zhang Y, Bokov A, Gelfond J, Soto V, Ikeno Y, Hubbard G, Diaz V, Sloane L, Maslin K, Treaster S, Réndon S, van Remmen H, Ward W, Javors M, Richardson A, Austad SN, Fischer K. Zhang Y, et al. J Gerontol A Biol Sci Med Sci. 2014 Feb;69(2):119-30. doi: 10.1093/gerona/glt056. Epub 2013 May 16. J Gerontol A Biol Sci Med Sci. 2014. PMID: 23682161 Free PMC article.
Target of rapamycin inhibition by rapamycin feeding has previously been shown to extend life in genetically heterogeneous mice. ...Survival was also improved by this late-life rapamycin feeding, and some pathol …
Target of rapamycin inhibition by rapamycin feeding has previously been shown to extend life in genetically
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