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Anti-virulence strategies to combat bacteria-mediated disease.
Rasko DA, Sperandio V. Rasko DA, et al. Nat Rev Drug Discov. 2010 Feb;9(2):117-28. doi: 10.1038/nrd3013. Epub 2010 Jan 18. Nat Rev Drug Discov. 2010. PMID: 20081869 Review.
Repression of bacterial motility by a novel fimbrial gene product.
Li X, Rasko DA, Lockatell CV, Johnson DE, Mobley HL. Li X, et al. EMBO J. 2001 Sep 3;20(17):4854-62. doi: 10.1093/emboj/20.17.4854. EMBO J. 2001. PMID: 11532949 Free PMC article.
Identification of DNA sequences from a second pathogenicity island of uropathogenic Escherichia coli CFT073: probes specific for uropathogenic populations.
Rasko DA, Phillips JA, Li X, Mobley HL. Rasko DA, et al. J Infect Dis. 2001 Oct 15;184(8):1041-9. doi: 10.1086/323602. Epub 2001 Sep 28. J Infect Dis. 2001. PMID: 11574920
Autotransporter genes pic and tsh are associated with Escherichia coli strains that cause acute pyelonephritis and are expressed during urinary tract infection.
Heimer SR, Rasko DA, Lockatell CV, Johnson DE, Mobley HL. Heimer SR, et al. Infect Immun. 2004 Jan;72(1):593-7. doi: 10.1128/iai.72.1.593-597.2004. Infect Immun. 2004. PMID: 14688142 Free PMC article.
Major structural differences and novel potential virulence mechanisms from the genomes of multiple campylobacter species.
Fouts DE, Mongodin EF, Mandrell RE, Miller WG, Rasko DA, Ravel J, Brinkac LM, DeBoy RT, Parker CT, Daugherty SC, Dodson RJ, Durkin AS, Madupu R, Sullivan SA, Shetty JU, Ayodeji MA, Shvartsbeyn A, Schatz MC, Badger JH, Fraser CM, Nelson KE. Fouts DE, et al. PLoS Biol. 2005 Jan;3(1):e15. doi: 10.1371/journal.pbio.0030015. Epub 2005 Jan 4. PLoS Biol. 2005. PMID: 15660156 Free PMC article.
The pangenome structure of Escherichia coli: comparative genomic analysis of E. coli commensal and pathogenic isolates.
Rasko DA, Rosovitz MJ, Myers GS, Mongodin EF, Fricke WF, Gajer P, Crabtree J, Sebaihia M, Thomson NR, Chaudhuri R, Henderson IR, Sperandio V, Ravel J. Rasko DA, et al. J Bacteriol. 2008 Oct;190(20):6881-93. doi: 10.1128/JB.00619-08. Epub 2008 Aug 1. J Bacteriol. 2008. PMID: 18676672 Free PMC article.
Targeting QseC signaling and virulence for antibiotic development.
Rasko DA, Moreira CG, Li de R, Reading NC, Ritchie JM, Waldor MK, Williams N, Taussig R, Wei S, Roth M, Hughes DT, Huntley JF, Fina MW, Falck JR, Sperandio V. Rasko DA, et al. Science. 2008 Aug 22;321(5892):1078-80. doi: 10.1126/science.1160354. Science. 2008. PMID: 18719281 Free PMC article.
Role of the K2 capsule in Escherichia coli urinary tract infection and serum resistance.
Buckles EL, Wang X, Lane MC, Lockatell CV, Johnson DE, Rasko DA, Mobley HL, Donnenberg MS. Buckles EL, et al. J Infect Dis. 2009 Jun 1;199(11):1689-97. doi: 10.1086/598524. J Infect Dis. 2009. PMID: 19432551 Free PMC article.
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