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The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation.
Poulsen ET, Nielsen NS, Scavenius C, Mogensen EH, Risør MW, Runager K, Lukassen MV, Rasmussen CB, Christiansen G, Richner M, Vorum H, Enghild JJ. Poulsen ET, et al. Among authors: rasmussen cb. J Biol Chem. 2019 Aug 2;294(31):11817-11828. doi: 10.1074/jbc.RA119.009050. Epub 2019 Jun 13. J Biol Chem. 2019. PMID: 31197037 Free PMC article.
Conservation of the Amyloid Interactome Across Diverse Fibrillar Structures.
Juhl DW, Risør MW, Scavenius C, Rasmussen CB, Otzen D, Nielsen NC, Enghild JJ. Juhl DW, et al. Among authors: rasmussen cb. Sci Rep. 2019 Mar 7;9(1):3863. doi: 10.1038/s41598-019-40483-z. Sci Rep. 2019. PMID: 30846764 Free PMC article.
Imperfect repeats in the functional amyloid protein FapC reduce the tendency to fragment during fibrillation.
Rasmussen CB, Christiansen G, Vad BS, Lynggaard C, Enghild JJ, Andreasen M, Otzen D. Rasmussen CB, et al. Protein Sci. 2019 Mar;28(3):633-642. doi: 10.1002/pro.3566. Epub 2019 Jan 12. Protein Sci. 2019. PMID: 30592554 Free PMC article.