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Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders.
Xu L, Carrer A, Zonta F, Qu Z, Ma P, Li S, Ceriani F, Buratto D, Crispino G, Zorzi V, Ziraldo G, Bruno F, Nardin C, Peres C, Mazzarda F, Salvatore AM, Raspa M, Scavizzi F, Chu Y, Xie S, Yang X, Liao J, Liu X, Wang W, Wang S, Yang G, Lerner RA, Mammano F. Xu L, et al. Among authors: raspa m. Front Mol Neurosci. 2017 Sep 22;10:298. doi: 10.3389/fnmol.2017.00298. eCollection 2017. Front Mol Neurosci. 2017. PMID: 29018324 Free PMC article.
Mouse Panx1 Is Dispensable for Hearing Acquisition and Auditory Function.
Zorzi V, Paciello F, Ziraldo G, Peres C, Mazzarda F, Nardin C, Pasquini M, Chiani F, Raspa M, Scavizzi F, Carrer A, Crispino G, Ciubotaru CD, Monyer H, Fetoni AR, M Salvatore A, Mammano F. Zorzi V, et al. Among authors: raspa m, m salvatore a. Front Mol Neurosci. 2017 Nov 28;10:379. doi: 10.3389/fnmol.2017.00379. eCollection 2017. Front Mol Neurosci. 2017. PMID: 29234270 Free PMC article.
Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway.
Fetoni AR, Zorzi V, Paciello F, Ziraldo G, Peres C, Raspa M, Scavizzi F, Salvatore AM, Crispino G, Tognola G, Gentile G, Spampinato AG, Cuccaro D, Guarnaccia M, Morello G, Van Camp G, Fransen E, Brumat M, Girotto G, Paludetti G, Gasparini P, Cavallaro S, Mammano F. Fetoni AR, et al. Among authors: raspa m. Redox Biol. 2018 Oct;19:301-317. doi: 10.1016/j.redox.2018.08.002. Epub 2018 Aug 7. Redox Biol. 2018. PMID: 30199819 Free PMC article.
A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice.
Kuang Y, Zorzi V, Buratto D, Ziraldo G, Mazzarda F, Peres C, Nardin C, Salvatore AM, Chiani F, Scavizzi F, Raspa M, Qiang M, Chu Y, Shi X, Li Y, Liu L, Shi Y, Zonta F, Yang G, Lerner RA, Mammano F. Kuang Y, et al. Among authors: raspa m. EBioMedicine. 2020 Jul;57:102825. doi: 10.1016/j.ebiom.2020.102825. Epub 2020 Jun 15. EBioMedicine. 2020. PMID: 32553574 Free PMC article.
Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca2+ signaling in non-sensory cells of the greater epithelial ridge in the developing cochlea.
Mazzarda F, D'Elia A, Massari R, De Ninno A, Bertani FR, Businaro L, Ziraldo G, Zorzi V, Nardin C, Peres C, Chiani F, Tettey-Matey A, Raspa M, Scavizzi F, Soluri A, Salvatore AM, Yang J, Mammano F. Mazzarda F, et al. Among authors: raspa m. Lab Chip. 2020 Aug 11;20(16):3011-3023. doi: 10.1039/d0lc00427h. Lab Chip. 2020. PMID: 32700707
141 results