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Chagas' heart disease.
Rassi A Jr, Rassi A, Little WC. Rassi A Jr, et al. Among authors: rassi a. Clin Cardiol. 2000 Dec;23(12):883-9. doi: 10.1002/clc.4960231205. Clin Cardiol. 2000. PMID: 11129673 Free PMC article. Review.
Chagas' disease is caused by a protozoan parasite, Trypanosoma cruzi, that is transmitted to humans through the feces of infected bloodsucking insects in endemic areas of Latin America, or occasionally by nonvectorial mechanisms, such as blood transfusion. ...The use of am …
Chagas' disease is caused by a protozoan parasite, Trypanosoma cruzi, that is transmitted to humans through the feces of infected blo …
Randomized Trial of Benznidazole for Chronic Chagas' Cardiomyopathy.
Morillo CA, Marin-Neto JA, Avezum A, Sosa-Estani S, Rassi A Jr, Rosas F, Villena E, Quiroz R, Bonilla R, Britto C, Guhl F, Velazquez E, Bonilla L, Meeks B, Rao-Melacini P, Pogue J, Mattos A, Lazdins J, Rassi A, Connolly SJ, Yusuf S; BENEFIT Investigators. Morillo CA, et al. Among authors: rassi a jr, rassi a. N Engl J Med. 2015 Oct;373(14):1295-306. doi: 10.1056/NEJMoa1507574. Epub 2015 Sep 1. N Engl J Med. 2015. PMID: 26323937 Clinical Trial.
METHODS: We conducted a prospective, multicenter, randomized study involving 2854 patients with Chagas' cardiomyopathy who received benznidazole or placebo for up to 80 days and were followed for a mean of 5.4 years. ...At baseline, a polymerase-chain-reactio …
METHODS: We conducted a prospective, multicenter, randomized study involving 2854 patients with Chagas' cardiomyopathy who received b …
A Latin American man with palpitations, dizziness, episodes of nonsustained ventricular tachycardia, and an apical aneurysm.
Rassi A Jr, Rassi A, Franco-Paredes C. Rassi A Jr, et al. Among authors: rassi a. PLoS Negl Trop Dis. 2011 Feb 22;5(2):e852. doi: 10.1371/journal.pntd.0000852. PLoS Negl Trop Dis. 2011. PMID: 21364964 Free PMC article. No abstract available.
Chagas disease.
Rassi A Jr, Rassi A, Marin-Neto JA. Rassi A Jr, et al. Among authors: rassi a. Lancet. 2010 Apr 17;375(9723):1388-402. doi: 10.1016/S0140-6736(10)60061-X. Lancet. 2010. PMID: 20399979 Review.
Chagas disease is a chronic, systemic, parasitic infection caused by the protozoan Trypanosoma cruzi, and was discovered in 1909. ...Although more effective trypanocidal drugs are needed, treatment with benznidazole (or nifurtimox) is reasonably safe and effective, and is …
Chagas disease is a chronic, systemic, parasitic infection caused by the protozoan Trypanosoma cruzi, and was discovered in 1909. ... …
Deficient regulatory T cell activity and low frequency of IL-17-producing T cells correlate with the extent of cardiomyopathy in human Chagas' disease.
Guedes PM, Gutierrez FR, Silva GK, Dellalibera-Joviliano R, Rodrigues GJ, Bendhack LM, Rassi A Jr, Rassi A, Schmidt A, Maciel BC, Marin Neto JA, Silva JS. Guedes PM, et al. Among authors: rassi a jr, rassi a. PLoS Negl Trop Dis. 2012;6(4):e1630. doi: 10.1371/journal.pntd.0001630. Epub 2012 Apr 24. PLoS Negl Trop Dis. 2012. PMID: 22545173 Free PMC article.
American trypanosomiasis (Chagas disease).
Rassi A Jr, Rassi A, Marcondes de Rezende J. Rassi A Jr, et al. Among authors: rassi a. Infect Dis Clin North Am. 2012 Jun;26(2):275-91. doi: 10.1016/j.idc.2012.03.002. Infect Dis Clin North Am. 2012. PMID: 22632639 Review.
Chagas disease, also known as American trypanosomiasis, is a chronic infection caused by Trypanosoma cruzi, a protozoan parasite. ...This article provides a brief update on the epidemiology, clinical manifestations, diagnosis, and treatment of Chagas disease. …
Chagas disease, also known as American trypanosomiasis, is a chronic infection caused by Trypanosoma cruzi, a protozoan parasi …
Predicting prognosis in patients with Chagas disease: why are the results of various studies so different?
Rassi A Jr, Rassi A. Rassi A Jr, et al. Among authors: rassi a. Int J Cardiol. 2010 Nov 5;145(1):64-5; author reply 66-7. doi: 10.1016/j.ijcard.2009.04.034. Epub 2009 May 9. Int J Cardiol. 2010. PMID: 19428129
The clinical course of Chagas disease is highly variable, and the identification of patients at risk of dying is a critical issue. In the last decades multiple factors, such as NYHA functional class III/IV, cardiomegaly, low ejection fraction, and non-sustained ventricular …
The clinical course of Chagas disease is highly variable, and the identification of patients at risk of dying is a critical issue. In …
Update on Chagas heart disease on the first centenary of its discovery.
Marin-Neto JA, Rassi A Jr. Marin-Neto JA, et al. Among authors: rassi a jr. Rev Esp Cardiol. 2009 Nov;62(11):1211-6. doi: 10.1016/s1885-5857(09)73346-8. Rev Esp Cardiol. 2009. PMID: 19889330 No abstract available.
Chagas heart disease: pathophysiologic mechanisms, prognostic factors and risk stratification.
Rassi A Jr, Rassi A, Marin-Neto JA. Rassi A Jr, et al. Among authors: rassi a. Mem Inst Oswaldo Cruz. 2009 Jul;104 Suppl 1:152-8. doi: 10.1590/s0074-02762009000900021. Mem Inst Oswaldo Cruz. 2009. PMID: 19753470
It poses a substantial public health burden due to high morbidity and mortality. CHD is also the most serious and frequent manifestation of chronic Chagas disease and appears in 20-40% of infected individuals between 10-30 years after the original acute infection. In recen …
It poses a substantial public health burden due to high morbidity and mortality. CHD is also the most serious and frequent manifestat …
Should tissue Doppler echocardiography be used to improve prediction of mortality risk in patients with Chagas cardiomyopathy?
Rassi A Jr, Rassi A, Correia LC. Rassi A Jr, et al. Among authors: rassi a. Int J Cardiol. 2011 May 19;149(1):134-5. doi: 10.1016/j.ijcard.2011.02.004. Epub 2011 Mar 11. Int J Cardiol. 2011. PMID: 21396724 No abstract available.
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