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Activation of the HIF pathway in cancer.
Maxwell PH, Pugh CW, Ratcliffe PJ. Maxwell PH, et al. Among authors: ratcliffe pj. Curr Opin Genet Dev. 2001 Jun;11(3):293-9. doi: 10.1016/s0959-437x(00)00193-3. Curr Opin Genet Dev. 2001. PMID: 11377966 Review.
Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences.
Ebert BL, Firth JD, Ratcliffe PJ. Ebert BL, et al. Among authors: ratcliffe pj. J Biol Chem. 1995 Dec 8;270(49):29083-9. doi: 10.1074/jbc.270.49.29083. J Biol Chem. 1995. PMID: 7493931
Hypoxic regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements.
Firth JD, Ebert BL, Ratcliffe PJ. Firth JD, et al. Among authors: ratcliffe pj. J Biol Chem. 1995 Sep 8;270(36):21021-7. doi: 10.1074/jbc.270.36.21021. J Biol Chem. 1995. PMID: 7673128
Diphenylene iodonium inhibits the induction of erythropoietin and other mammalian genes by hypoxia. Implications for the mechanism of oxygen sensing.
Gleadle JM, Ebert BL, Ratcliffe PJ. Gleadle JM, et al. Among authors: ratcliffe pj. Eur J Biochem. 1995 Nov 15;234(1):92-9. doi: 10.1111/j.1432-1033.1995.092_c.x. Eur J Biochem. 1995. PMID: 8529674
The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells.
Wood SM, Gleadle JM, Pugh CW, Hankinson O, Ratcliffe PJ. Wood SM, et al. Among authors: ratcliffe pj. J Biol Chem. 1996 Jun 21;271(25):15117-23. doi: 10.1074/jbc.271.25.15117. J Biol Chem. 1996. PMID: 8662957
Drosophila melanogaster SL2 cells contain a hypoxically inducible DNA binding complex which recognises mammalian HIF-binding sites.
Nagao M, Ebert BL, Ratcliffe PJ, Pugh CW. Nagao M, et al. Among authors: ratcliffe pj. FEBS Lett. 1996 Jun 3;387(2-3):161-6. doi: 10.1016/0014-5793(96)00484-x. FEBS Lett. 1996. PMID: 8674541
Identification of hypoxically inducible mRNAs in HeLa cells using differential-display PCR. Role of hypoxia-inducible factor-1.
O'Rourke JF, Pugh CW, Bartlett SM, Ratcliffe PJ. O'Rourke JF, et al. Among authors: ratcliffe pj. Eur J Biochem. 1996 Oct 15;241(2):403-10. doi: 10.1111/j.1432-1033.1996.00403.x. Eur J Biochem. 1996. PMID: 8917436
Induction of hypoxia-inducible factor-1, erythropoietin, vascular endothelial growth factor, and glucose transporter-1 by hypoxia: evidence against a regulatory role for Src kinase.
Gleadle JM, Ratcliffe PJ. Gleadle JM, et al. Among authors: ratcliffe pj. Blood. 1997 Jan 15;89(2):503-9. Blood. 1997. PMID: 9002952
Oxygen regulated gene expression: erythropoietin as a model system.
Ratcliffe PJ, Ebert BL, Firth JD, Gleadle JM, Maxwell PH, Nagao M, O'Rourke JF, Pugh CW, Wood SM. Ratcliffe PJ, et al. Kidney Int. 1997 Feb;51(2):514-26. doi: 10.1038/ki.1997.72. Kidney Int. 1997. PMID: 9027732 Review. No abstract available.
Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit.
Pugh CW, O'Rourke JF, Nagao M, Gleadle JM, Ratcliffe PJ. Pugh CW, et al. Among authors: ratcliffe pj. J Biol Chem. 1997 Apr 25;272(17):11205-14. doi: 10.1074/jbc.272.17.11205. J Biol Chem. 1997. PMID: 9111021
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