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MAP kinase signalling pathways in cancer.
Dhillon AS, Hagan S, Rath O, Kolch W. Dhillon AS, et al. Among authors: rath o. Oncogene. 2007 May 14;26(22):3279-90. doi: 10.1038/sj.onc.1210421. Oncogene. 2007. PMID: 17496922 Review.
LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation.
Mardilovich K, Baugh M, Crighton D, Kowalczyk D, Gabrielsen M, Munro J, Croft DR, Lourenco F, James D, Kalna G, McGarry L, Rath O, Shanks E, Garnett MJ, McDermott U, Brookfield J, Charles M, Hammonds T, Olson MF. Mardilovich K, et al. Among authors: rath o. Oncotarget. 2015 Nov 17;6(36):38469-86. doi: 10.18632/oncotarget.6288. Oncotarget. 2015. PMID: 26540348 Free PMC article.
Kinesins and cancer.
Rath O, Kozielski F. Rath O, et al. Nat Rev Cancer. 2012 Jul 24;12(8):527-39. doi: 10.1038/nrc3310. Nat Rev Cancer. 2012. PMID: 22825217 Review.
Regulation of RKIP binding to the N-region of the Raf-1 kinase.
Park S, Rath O, Beach S, Xiang X, Kelly SM, Luo Z, Kolch W, Yeung KC. Park S, et al. Among authors: rath o. FEBS Lett. 2006 Nov 27;580(27):6405-12. doi: 10.1016/j.febslet.2006.10.054. Epub 2006 Nov 3. FEBS Lett. 2006. PMID: 17097642 Free PMC article.
Functional roles of multiple feedback loops in extracellular signal-regulated kinase and Wnt signaling pathways that regulate epithelial-mesenchymal transition.
Shin SY, Rath O, Zebisch A, Choo SM, Kolch W, Cho KH. Shin SY, et al. Among authors: rath o. Cancer Res. 2010 Sep 1;70(17):6715-24. doi: 10.1158/0008-5472.CAN-10-1377. Epub 2010 Aug 24. Cancer Res. 2010. PMID: 20736375 Free PMC article.
Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity.
von Thun A, Preisinger C, Rath O, Schwarz JP, Ward C, Monsefi N, Rodríguez J, Garcia-Munoz A, Birtwistle M, Bienvenut W, Anderson KI, Kolch W, von Kriegsheim A. von Thun A, et al. Among authors: rath o. Mol Cell Biol. 2013 Nov;33(22):4526-37. doi: 10.1128/MCB.00585-13. Epub 2013 Sep 16. Mol Cell Biol. 2013. PMID: 24043311 Free PMC article.
Regulation of human myoblast differentiation by PEBP4.
Garcia R, Grindlay J, Rath O, Fee F, Kolch W. Garcia R, et al. Among authors: rath o. EMBO Rep. 2009 Mar;10(3):278-84. doi: 10.1038/embor.2009.4. Epub 2009 Feb 6. EMBO Rep. 2009. PMID: 19197339 Free PMC article.
The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK.
Rath O, Park S, Tang HH, Banfield MJ, Brady RL, Lee YC, Dignam JD, Sedivy JM, Kolch W, Yeung KC. Rath O, et al. Cell Signal. 2008 May;20(5):935-41. doi: 10.1016/j.cellsig.2008.01.012. Epub 2008 Jan 24. Cell Signal. 2008. PMID: 18294816
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