Rathmell JC - Search Results

1

Activated lymphocytes as a metabolic model for carcinogenesis.

Macintyre AN, Rathmell JC. Macintyre AN, et al. Among authors: rathmell jc. Cancer Metab. 2013 Jan 23;1(1):5. doi: 10.1186/2049-3002-1-5. Cancer Metab. 2013. PMID: 24280044 Free PMC article.

2

Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis.

Altman BJ, Jacobs SR, Mason EF, Michalek RD, MacIntyre AN, Coloff JL, Ilkayeva O, Jia W, He YW, Rathmell JC. Altman BJ, et al. Among authors: rathmell jc. Oncogene. 2011 Apr 21;30(16):1855-67. doi: 10.1038/onc.2010.561. Epub 2010 Dec 13. Oncogene. 2011. PMID: 21151168 Free PMC article.

3

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

Michalek RD, Gerriets VA, Jacobs SR, Macintyre AN, MacIver NJ, Mason EF, Sullivan SA, Nichols AG, Rathmell JC. Michalek RD, et al. Among authors: rathmell jc. J Immunol. 2011 Mar 15;186(6):3299-303. doi: 10.4049/jimmunol.1003613. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317389 Free PMC article.

4

Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.

Coloff JL, Macintyre AN, Nichols AG, Liu T, Gallo CA, Plas DR, Rathmell JC. Coloff JL, et al. Among authors: rathmell jc. Cancer Res. 2011 Aug 1;71(15):5204-13. doi: 10.1158/0008-5472.CAN-10-4531. Epub 2011 Jun 13. Cancer Res. 2011. PMID: 21670080 Free PMC article.

5

PKM2 and the tricky balance of growth and energy in cancer.

Macintyre AN, Rathmell JC. Macintyre AN, et al. Among authors: rathmell jc. Mol Cell. 2011 Jun 24;42(6):713-4. doi: 10.1016/j.molcel.2011.06.003. Mol Cell. 2011. PMID: 21700216 Free PMC article.

6

Metabolic regulation of T lymphocytes.

MacIver NJ, Michalek RD, Rathmell JC. MacIver NJ, et al. Among authors: rathmell jc. Annu Rev Immunol. 2013;31:259-83. doi: 10.1146/annurev-immunol-032712-095956. Epub 2013 Jan 3. Annu Rev Immunol. 2013. PMID: 23298210 Free PMC article. Review.

7

Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.

Kurokawa M, Ito T, Yang CS, Zhao C, Macintyre AN, Rizzieri DA, Rathmell JC, Deininger MW, Reya T, Kornbluth S. Kurokawa M, et al. Among authors: rathmell jc. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2300-5. doi: 10.1073/pnas.1206551110. Epub 2013 Jan 16. Proc Natl Acad Sci U S A. 2013. PMID: 23324740 Free PMC article.

8

Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype.

Freemerman AJ, Johnson AR, Sacks GN, Milner JJ, Kirk EL, Troester MA, Macintyre AN, Goraksha-Hicks P, Rathmell JC, Makowski L. Freemerman AJ, et al. Among authors: rathmell jc. J Biol Chem. 2014 Mar 14;289(11):7884-96. doi: 10.1074/jbc.M113.522037. Epub 2014 Feb 3. J Biol Chem. 2014. PMID: 24492615 Free PMC article.

9

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.

Macintyre AN, Gerriets VA, Nichols AG, Michalek RD, Rudolph MC, Deoliveira D, Anderson SM, Abel ED, Chen BJ, Hale LP, Rathmell JC. Macintyre AN, et al. Among authors: rathmell jc. Cell Metab. 2014 Jul 1;20(1):61-72. doi: 10.1016/j.cmet.2014.05.004. Epub 2014 Jun 12. Cell Metab. 2014. PMID: 24930970 Free PMC article.

10

Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells.

Cao Y, Rathmell JC, Macintyre AN. Cao Y, et al. Among authors: rathmell jc. PLoS One. 2014 Aug 4;9(8):e104104. doi: 10.1371/journal.pone.0104104. eCollection 2014. PLoS One. 2014. PMID: 25090630 Free PMC article.

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