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Quality by design for biopharmaceuticals.
Rathore AS, Winkle H. Rathore AS, et al. Nat Biotechnol. 2009 Jan;27(1):26-34. doi: 10.1038/nbt0109-26. Nat Biotechnol. 2009. PMID: 19131992 No abstract available.
Case study and application of process analytical technology (PAT) towards bioprocessing: Use of tryptophan fluorescence as at-line tool for making pooling decisions for process chromatography.
Rathore AS, Li X, Bartkowski W, Sharma A, Lu Y. Rathore AS, et al. Biotechnol Prog. 2009 Sep-Oct;25(5):1433-9. doi: 10.1002/btpr.212. Biotechnol Prog. 2009. PMID: 19725111
It is significantly faster than the alternative of fractionation, offline analysis followed by pooling. Although the method as presented here is not an online method, this technique may offer better resolution for certain applications and may be a more optimal approach …
It is significantly faster than the alternative of fractionation, offline analysis followed by pooling. Although the method as presen …
283 results