Ratnam M - Search Results

1

The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells.

Patki M, Chari V, Sivakumaran S, Gonit M, Trumbly R, Ratnam M. Patki M, et al. Among authors: ratnam m. J Biol Chem. 2013 Apr 19;288(16):11047-65. doi: 10.1074/jbc.M112.438473. Epub 2013 Feb 20. J Biol Chem. 2013. PMID: 23426362 Free PMC article.

2

Restoration of the cellular secretory milieu overrides androgen dependence of in vivo generated castration resistant prostate cancer cells overexpressing the androgen receptor.

Patki M, Huang Y, Ratnam M. Patki M, et al. Among authors: ratnam m. Biochem Biophys Res Commun. 2016 Jul 22;476(2):69-74. doi: 10.1016/j.bbrc.2016.05.058. Epub 2016 May 12. Biochem Biophys Res Commun. 2016. PMID: 27179779 Free article.

3

The Amino-terminal Domain of the Androgen Receptor Co-opts Extracellular Signal-regulated Kinase (ERK) Docking Sites in ELK1 Protein to Induce Sustained Gene Activation That Supports Prostate Cancer Cell Growth.

Rosati R, Patki M, Chari V, Dakshnamurthy S, McFall T, Saxton J, Kidder BL, Shaw PE, Ratnam M. Rosati R, et al. Among authors: ratnam m. J Biol Chem. 2016 Dec 9;291(50):25983-25998. doi: 10.1074/jbc.M116.745596. Epub 2016 Oct 28. J Biol Chem. 2016. PMID: 27793987 Free PMC article.

4

During hormone depletion or tamoxifen treatment of breast cancer cells the estrogen receptor apoprotein supports cell cycling through the retinoic acid receptor α1 apoprotein.

Salazar MD, Ratnam M, Patki M, Kisovic I, Trumbly R, Iman M, Ratnam M. Salazar MD, et al. Among authors: ratnam m. Breast Cancer Res. 2011 Feb 7;13(1):R18. doi: 10.1186/bcr2827. Breast Cancer Res. 2011. PMID: 21299862 Free PMC article.

5

Hormone depletion-insensitivity of prostate cancer cells is supported by the AR without binding to classical response elements.

Gonit M, Zhang J, Salazar Md, Cui H, Shatnawi A, Trumbly R, Ratnam M. Gonit M, et al. Among authors: ratnam m. Mol Endocrinol. 2011 Apr;25(4):621-34. doi: 10.1210/me.2010-0409. Epub 2011 Feb 17. Mol Endocrinol. 2011. PMID: 21330406 Free PMC article.

6

Differential effects of estrogen-dependent transactivation vs. transrepression by the estrogen receptor on invasiveness of HER2 overexpressing breast cancer cells.

Patki M, Salazar Md, Trumbly R, Ratnam M. Patki M, et al. Among authors: ratnam m. Biochem Biophys Res Commun. 2015 Feb 13;457(3):404-11. doi: 10.1016/j.bbrc.2015.01.004. Epub 2015 Jan 9. Biochem Biophys Res Commun. 2015. PMID: 25582774 Free PMC article.

7

Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges.

McFall T, Patki M, Rosati R, Ratnam M. McFall T, et al. Among authors: ratnam m. Oncotarget. 2015 Oct 20;6(32):33146-64. doi: 10.18632/oncotarget.5082. Oncotarget. 2015. PMID: 26356672 Free PMC article.

8

Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer Cells.

Rosati R, Chen B, Patki M, McFall T, Ou S, Heath E, Ratnam M, Qin Z. Rosati R, et al. Among authors: ratnam m. Mol Pharmacol. 2016 Sep;90(3):225-37. doi: 10.1124/mol.116.103416. Epub 2016 Jul 5. Mol Pharmacol. 2016. PMID: 27382012 Free PMC article.

9

C/EBPalpha redirects androgen receptor signaling through a unique bimodal interaction.

Zhang J, Gonit M, Salazar MD, Shatnawi A, Shemshedini L, Trumbly R, Ratnam M. Zhang J, et al. Among authors: ratnam m. Oncogene. 2010 Feb 4;29(5):723-38. doi: 10.1038/onc.2009.373. Epub 2009 Nov 9. Oncogene. 2010. PMID: 19901962 Free PMC article.

10

Androgen activation of the folate receptor α gene through partial tethering of the androgen receptor by C/EBPα.

Sivakumaran S, Zhang J, Kelley KM, Gonit M, Hao H, Ratnam M. Sivakumaran S, et al. Among authors: ratnam m. J Steroid Biochem Mol Biol. 2010 Nov;122(5):333-40. doi: 10.1016/j.jsbmb.2010.08.008. Epub 2010 Sep 15. J Steroid Biochem Mol Biol. 2010. PMID: 20817090 Free PMC article.

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