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Defective transcription elongation in a subset of cancers confers immunotherapy resistance.
Modur V, Singh N, Mohanty V, Chung E, Muhammad B, Choi K, Chen X, Chetal K, Ratner N, Salomonis N, Weirauch MT, Waltz S, Huang G, Privette-Vinnedge L, Park JS, Janssen EM, Komurov K. Modur V, et al. Among authors: ratner n. Nat Commun. 2018 Oct 23;9(1):4410. doi: 10.1038/s41467-018-06810-0. Nat Commun. 2018. PMID: 30353012 Free PMC article.
Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas.
Dombi E, Baldwin A, Marcus LJ, Fisher MJ, Weiss B, Kim A, Whitcomb P, Martin S, Aschbacher-Smith LE, Rizvi TA, Wu J, Ershler R, Wolters P, Therrien J, Glod J, Belasco JB, Schorry E, Brofferio A, Starosta AJ, Gillespie A, Doyle AL, Ratner N, Widemann BC. Dombi E, et al. Among authors: ratner n. N Engl J Med. 2016 Dec 29;375(26):2550-2560. doi: 10.1056/NEJMoa1605943. N Engl J Med. 2016. PMID: 28029918 Free PMC article. Clinical Trial.
Cxcr3-expressing leukocytes are necessary for neurofibroma formation in mice.
Fletcher JS, Wu J, Jessen WJ, Pundavela J, Miller JA, Dombi E, Kim MO, Rizvi TA, Chetal K, Salomonis N, Ratner N. Fletcher JS, et al. Among authors: ratner n. JCI Insight. 2019 Feb 7;4(3):e98601. doi: 10.1172/jci.insight.98601. JCI Insight. 2019. PMID: 30728335 Free PMC article.
Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1.
Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, Stemmer-Rachamimov AO, Fahrenkrug SC, Gutmann DH, Giovannini M, Moertel CL, Largaespada DA, Watson AL. Isakson SH, et al. Among authors: ratner n. Commun Biol. 2018 Oct 2;1:158. doi: 10.1038/s42003-018-0163-y. eCollection 2018. Commun Biol. 2018. PMID: 30302402 Free PMC article.
298 results