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Carbamoyl phosphate synthetase: a tunnel runs through it.
Holden HM, Thoden JB, Raushel FM. Holden HM, et al. Among authors: raushel fm. Curr Opin Struct Biol. 1998 Dec;8(6):679-85. doi: 10.1016/s0959-440x(98)80086-9. Curr Opin Struct Biol. 1998. PMID: 9914247 Review.
The binding of substrate analogs to phosphotriesterase.
Benning MM, Hong SB, Raushel FM, Holden HM. Benning MM, et al. Among authors: raushel fm. J Biol Chem. 2000 Sep 29;275(39):30556-60. doi: 10.1074/jbc.M003852200. J Biol Chem. 2000. PMID: 10871616
Restricted passage of reaction intermediates through the ammonia tunnel of carbamoyl phosphate synthetase.
Huang X, Raushel FM. Huang X, et al. Among authors: raushel fm. J Biol Chem. 2000 Aug 25;275(34):26233-40. doi: 10.1074/jbc.275.34.26233. J Biol Chem. 2000. PMID: 10950966
A combined theoretical and experimental study of the ammonia tunnel in carbamoyl phosphate synthetase.
Fan Y, Lund L, Shao Q, Gao YQ, Raushel FM. Fan Y, et al. Among authors: raushel fm. J Am Chem Soc. 2009 Jul 29;131(29):10211-9. doi: 10.1021/ja902557r. J Am Chem Soc. 2009. PMID: 19569682 Free PMC article.
Tunneling of intermediates in enzyme-catalyzed reactions.
Weeks A, Lund L, Raushel FM. Weeks A, et al. Among authors: raushel fm. Curr Opin Chem Biol. 2006 Oct;10(5):465-72. doi: 10.1016/j.cbpa.2006.08.008. Epub 2006 Aug 23. Curr Opin Chem Biol. 2006. PMID: 16931112 Review.
Access to the carbamate tunnel of carbamoyl phosphate synthetase.
Kim J, Raushel FM. Kim J, et al. Among authors: raushel fm. Arch Biochem Biophys. 2004 May 1;425(1):33-41. doi: 10.1016/j.abb.2004.02.031. Arch Biochem Biophys. 2004. PMID: 15081891
Inactivation of the amidotransferase activity of carbamoyl phosphate synthetase by the antibiotic acivicin.
Miles BW, Thoden JB, Holden HM, Raushel FM. Miles BW, et al. Among authors: raushel fm. J Biol Chem. 2002 Feb 8;277(6):4368-73. doi: 10.1074/jbc.M108582200. Epub 2001 Nov 29. J Biol Chem. 2002. PMID: 11729189
Dissection of the conduit for allosteric control of carbamoyl phosphate synthetase by ornithine.
Pierrat OA, Javid-Majd F, Raushel FM. Pierrat OA, et al. Among authors: raushel fm. Arch Biochem Biophys. 2002 Apr 1;400(1):26-33. doi: 10.1006/abbi.2002.2768. Arch Biochem Biophys. 2002. PMID: 11913967
Functional significance of Glu-77 and Tyr-137 within the active site of isoaspartyl dipeptidase.
Martí-Arbona R, Thoden JB, Holden HM, Raushel FM. Martí-Arbona R, et al. Among authors: raushel fm. Bioorg Chem. 2005 Dec;33(6):448-58. doi: 10.1016/j.bioorg.2005.10.002. Epub 2005 Nov 11. Bioorg Chem. 2005. PMID: 16289685
Long-range allosteric transitions in carbamoyl phosphate synthetase.
Thoden JB, Huang X, Kim J, Raushel FM, Holden HM. Thoden JB, et al. Among authors: raushel fm. Protein Sci. 2004 Sep;13(9):2398-405. doi: 10.1110/ps.04822704. Protein Sci. 2004. PMID: 15322282 Free PMC article.
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