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End-Binding E3 Ubiquitin Ligases Enable Protease Signaling.
Ravalin M, Basu K, Gestwicki JE, Craik CS. Ravalin M, et al. ACS Chem Biol. 2021 Nov 19;16(11):2047-2056. doi: 10.1021/acschembio.9b00621. Epub 2019 Nov 20. ACS Chem Biol. 2021. PMID: 31714737 Free PMC article. Review.
Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.
Ravalin M, Theofilas P, Basu K, Opoku-Nsiah KA, Assimon VA, Medina-Cleghorn D, Chen YF, Bohn MF, Arkin M, Grinberg LT, Craik CS, Gestwicki JE. Ravalin M, et al. Nat Chem Biol. 2019 Aug;15(8):786-794. doi: 10.1038/s41589-019-0322-6. Epub 2019 Jul 18. Nat Chem Biol. 2019. PMID: 31320752 Free PMC article.