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Skeletal muscle α-actin diseases (actinopathies): pathology and mechanisms.
Nowak KJ, Ravenscroft G, Laing NG. Nowak KJ, et al. Among authors: ravenscroft g. Acta Neuropathol. 2013 Jan;125(1):19-32. doi: 10.1007/s00401-012-1019-z. Epub 2012 Jul 24. Acta Neuropathol. 2013. PMID: 22825594 Review.
Dissociated flexor digitorum brevis myofiber culture system--a more mature muscle culture system.
Ravenscroft G, Nowak KJ, Jackaman C, Clément S, Lyons MA, Gallagher S, Bakker AJ, Laing NG. Ravenscroft G, et al. Cell Motil Cytoskeleton. 2007 Oct;64(10):727-38. doi: 10.1002/cm.20223. Cell Motil Cytoskeleton. 2007. PMID: 17654606
Novel application of flow cytometry: determination of muscle fiber types and protein levels in whole murine skeletal muscles and heart.
Jackaman C, Nowak KJ, Ravenscroft G, Lim EM, Clément S, Laing NG. Jackaman C, et al. Among authors: ravenscroft g. Cell Motil Cytoskeleton. 2007 Dec;64(12):914-25. doi: 10.1002/cm.20239. Cell Motil Cytoskeleton. 2007. PMID: 17922482
Expression of cardiac alpha-actin spares extraocular muscles in skeletal muscle alpha-actin diseases--quantification of striated alpha-actins by MRM-mass spectrometry.
Ravenscroft G, Colley SM, Walker KR, Clement S, Bringans S, Lipscombe R, Fabian VA, Laing NG, Nowak KJ. Ravenscroft G, et al. Neuromuscul Disord. 2008 Dec;18(12):953-8. doi: 10.1016/j.nmd.2008.09.010. Epub 2008 Oct 25. Neuromuscul Disord. 2008. PMID: 18952430
Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.
Nowak KJ, Ravenscroft G, Jackaman C, Filipovska A, Davies SM, Lim EM, Squire SE, Potter AC, Baker E, Clément S, Sewry CA, Fabian V, Crawford K, Lessard JL, Griffiths LM, Papadimitriou JM, Shen Y, Morahan G, Bakker AJ, Davies KE, Laing NG. Nowak KJ, et al. Among authors: ravenscroft g. J Cell Biol. 2009 Jun 1;185(5):903-15. doi: 10.1083/jcb.200812132. Epub 2009 May 25. J Cell Biol. 2009. PMID: 19468071 Free PMC article.
A novel ACTA1 mutation resulting in a severe congenital myopathy with nemaline bodies, intranuclear rods and type I fibre predominance.
Ravenscroft G, Wilmshurst JM, Pillay K, Sivadorai P, Wallefeld W, Nowak KJ, Laing NG. Ravenscroft G, et al. Neuromuscul Disord. 2011 Jan;21(1):31-6. doi: 10.1016/j.nmd.2010.08.005. Epub 2010 Sep 17. Neuromuscul Disord. 2011. PMID: 20850316
Mouse models of dominant ACTA1 disease recapitulate human disease and provide insight into therapies.
Ravenscroft G, Jackaman C, Bringans S, Papadimitriou JM, Griffiths LM, McNamara E, Bakker AJ, Davies KE, Laing NG, Nowak KJ. Ravenscroft G, et al. Brain. 2011 Apr;134(Pt 4):1101-15. doi: 10.1093/brain/awr004. Epub 2011 Feb 8. Brain. 2011. PMID: 21303860
Mutations in the N-terminal actin-binding domain of filamin C cause a distal myopathy.
Duff RM, Tay V, Hackman P, Ravenscroft G, McLean C, Kennedy P, Steinbach A, Schöffler W, van der Ven PFM, Fürst DO, Song J, Djinović-Carugo K, Penttilä S, Raheem O, Reardon K, Malandrini A, Gambelli S, Villanova M, Nowak KJ, Williams DR, Landers JE, Brown RH Jr, Udd B, Laing NG. Duff RM, et al. Among authors: ravenscroft g. Am J Hum Genet. 2011 Jun 10;88(6):729-740. doi: 10.1016/j.ajhg.2011.04.021. Epub 2011 May 27. Am J Hum Genet. 2011. PMID: 21620354 Free PMC article.
Fetal akinesia: review of the genetics of the neuromuscular causes.
Ravenscroft G, Sollis E, Charles AK, North KN, Baynam G, Laing NG. Ravenscroft G, et al. J Med Genet. 2011 Dec;48(12):793-801. doi: 10.1136/jmedgenet-2011-100211. Epub 2011 Oct 7. J Med Genet. 2011. PMID: 21984750 Review.
Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression.
Ravenscroft G, Jackaman C, Sewry CA, McNamara E, Squire SE, Potter AC, Papadimitriou J, Griffiths LM, Bakker AJ, Davies KE, Laing NG, Nowak KJ. Ravenscroft G, et al. PLoS One. 2011;6(12):e28699. doi: 10.1371/journal.pone.0028699. Epub 2011 Dec 9. PLoS One. 2011. PMID: 22174871 Free PMC article.
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