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A minor tyrosine phosphorylation site located within the CAIN domain plays a critical role in regulating tissue-specific transformation by erbB kinase.
Chang CM, Shu HK, Ravi L, Pelley RJ, Shu H, Kung HJ. Chang CM, et al. J Virol. 1995 Feb;69(2):1172-80. doi: 10.1128/JVI.69.2.1172-1180.1995. J Virol. 1995. PMID: 7815495 Free PMC article.
Modulation of erbB kinase activity and oncogenic potential by single point mutations in the glycine loop of the catalytic domain.
Shu HK, Chang CM, Ravi L, Ling L, Castellano CM, Walter E, Pelley RJ, Kung HJ. Shu HK, et al. Mol Cell Biol. 1994 Oct;14(10):6868-78. doi: 10.1128/mcb.14.10.6868. Mol Cell Biol. 1994. PMID: 7935404 Free PMC article.
HLTF gene silencing in human colon cancer.
Moinova HR, Chen WD, Shen L, Smiraglia D, Olechnowicz J, Ravi L, Kasturi L, Myeroff L, Plass C, Parsons R, Minna J, Willson JK, Green SB, Issa JP, Markowitz SD. Moinova HR, et al. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4562-7. doi: 10.1073/pnas.062459899. Epub 2002 Mar 19. Proc Natl Acad Sci U S A. 2002. PMID: 11904375 Free PMC article.
Assembly and deacetylation of N-acetylglucosaminyl-plasmanylinositol in normal and affected paroxysmal nocturnal hemoglobinuria cells.
Hirose S, Ravi L, Hazra SV, Medof ME. Hirose S, et al. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3762-6. doi: 10.1073/pnas.88.9.3762. Proc Natl Acad Sci U S A. 1991. PMID: 1708886 Free PMC article.
Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.
Guda K, Moinova H, He J, Jamison O, Ravi L, Natale L, Lutterbaugh J, Lawrence E, Lewis S, Willson JK, Lowe JB, Wiesner GL, Parmigiani G, Barnholtz-Sloan J, Dawson DW, Velculescu VE, Kinzler KW, Papadopoulos N, Vogelstein B, Willis J, Gerken TA, Markowitz SD. Guda K, et al. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12921-5. doi: 10.1073/pnas.0901454106. Epub 2009 Jul 17. Proc Natl Acad Sci U S A. 2009. PMID: 19617566 Free PMC article.
Aberrant vimentin methylation is characteristic of upper gastrointestinal pathologies.
Moinova H, Leidner RS, Ravi L, Lutterbaugh J, Barnholtz-Sloan JS, Chen Y, Chak A, Markowitz SD, Willis JE. Moinova H, et al. Cancer Epidemiol Biomarkers Prev. 2012 Apr;21(4):594-600. doi: 10.1158/1055-9965.EPI-11-1060. Epub 2012 Feb 7. Cancer Epidemiol Biomarkers Prev. 2012. PMID: 22315367 Free PMC article.
Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance.
Guda K, Fink SP, Milne GL, Molyneaux N, Ravi L, Lewis SM, Dannenberg AJ, Montgomery CG, Zhang S, Willis J, Wiesner GL, Markowitz SD. Guda K, et al. Cancer Prev Res (Phila). 2014 Aug;7(8):805-12. doi: 10.1158/1940-6207.CAPR-14-0108. Epub 2014 May 16. Cancer Prev Res (Phila). 2014. PMID: 24838973 Free PMC article.
Novel recurrently mutated genes in African American colon cancers.
Guda K, Veigl ML, Varadan V, Nosrati A, Ravi L, Lutterbaugh J, Beard L, Willson JK, Sedwick WD, Wang ZJ, Molyneaux N, Miron A, Adams MD, Elston RC, Markowitz SD, Willis JE. Guda K, et al. Proc Natl Acad Sci U S A. 2015 Jan 27;112(4):1149-54. doi: 10.1073/pnas.1417064112. Epub 2015 Jan 12. Proc Natl Acad Sci U S A. 2015. PMID: 25583493 Free PMC article. Clinical Trial.
Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer.
Venkitachalam S, Revoredo L, Varadan V, Fecteau RE, Ravi L, Lutterbaugh J, Markowitz SD, Willis JE, Gerken TA, Guda K. Venkitachalam S, et al. Among authors: ravi l. Sci Rep. 2016 Mar 23;6:23642. doi: 10.1038/srep23642. Sci Rep. 2016. PMID: 27004849 Free PMC article.
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