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An ARC light on lipid metabolism.
Rawson RB. Rawson RB. Cell Metab. 2006 Sep;4(3):181-3. doi: 10.1016/j.cmet.2006.08.008. Cell Metab. 2006. PMID: 16950135 Free article. Review.
Fatty acid auxotrophy in Drosophila larvae lacking SREBP.
Kunte AS, Matthews KA, Rawson RB. Kunte AS, et al. Cell Metab. 2006 Jun;3(6):439-48. doi: 10.1016/j.cmet.2006.04.011. Cell Metab. 2006. PMID: 16753579
Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Sever N, Lee PC, Song BL, Rawson RB, Debose-Boyd RA. Sever N, et al. J Biol Chem. 2004 Oct 8;279(41):43136-47. doi: 10.1074/jbc.M406406200. Epub 2004 Jul 7. J Biol Chem. 2004. PMID: 15247248
The SREBP pathway--insights from Insigs and insects.
Rawson RB. Rawson RB. Nat Rev Mol Cell Biol. 2003 Aug;4(8):631-40. doi: 10.1038/nrm1174. Nat Rev Mol Cell Biol. 2003. PMID: 12923525 Review.
Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs.
Dobrosotskaya IY, Goldstein JL, Brown MS, Rawson RB. Dobrosotskaya IY, et al. J Biol Chem. 2003 Sep 12;278(37):35837-43. doi: 10.1074/jbc.M306476200. Epub 2003 Jul 3. J Biol Chem. 2003. PMID: 12842885
Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.
Yabe D, Xia ZP, Adams CM, Rawson RB. Yabe D, et al. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16672-7. doi: 10.1073/pnas.262669399. Epub 2002 Dec 13. Proc Natl Acad Sci U S A. 2002. PMID: 12482938 Free PMC article.
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