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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T. Lachner M, et al. Among authors: rea s. Nature. 2001 Mar 1;410(6824):116-20. doi: 10.1038/35065132. Nature. 2001. PMID: 11242053
MSL proteins and the regulation of gene expression.
Rea S, Akhtar A. Rea S, et al. Curr Top Microbiol Immunol. 2006;310:117-40. doi: 10.1007/3-540-31181-5_7. Curr Top Microbiol Immunol. 2006. PMID: 16909909 Review.
Regulation of chromatin structure by site-specific histone H3 methyltransferases.
Rea S, Eisenhaber F, O'Carroll D, Strahl BD, Sun ZW, Schmid M, Opravil S, Mechtler K, Ponting CP, Allis CD, Jenuwein T. Rea S, et al. Nature. 2000 Aug 10;406(6796):593-9. doi: 10.1038/35020506. Nature. 2000. PMID: 10949293
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression.
O'Carroll D, Scherthan H, Peters AH, Opravil S, Haynes AR, Laible G, Rea S, Schmid M, Lebersorger A, Jerratsch M, Sattler L, Mattei MG, Denny P, Brown SD, Schweizer D, Jenuwein T. O'Carroll D, et al. Among authors: rea s. Mol Cell Biol. 2000 Dec;20(24):9423-33. doi: 10.1128/mcb.20.24.9423-9433.2000. Mol Cell Biol. 2000. PMID: 11094092 Free PMC article.
Males absent on the first (MOF): from flies to humans.
Rea S, Xouri G, Akhtar A. Rea S, et al. Oncogene. 2007 Aug 13;26(37):5385-94. doi: 10.1038/sj.onc.1210607. Oncogene. 2007. PMID: 17694080 Review.
Moreover, hMOF is involved in ATM activation in response to DNA damage and acetylation of p53 by hMOF influences the cell's decision to undergo apoptosis instead of a cell cycle arrest. ...
Moreover, hMOF is involved in ATM activation in response to DNA damage and acetylation of p53 by hMOF influences the cell's decision …
Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.
Schotta G, Ebert A, Krauss V, Fischer A, Hoffmann J, Rea S, Jenuwein T, Dorn R, Reuter G. Schotta G, et al. Among authors: rea s. EMBO J. 2002 Mar 1;21(5):1121-31. doi: 10.1093/emboj/21.5.1121. EMBO J. 2002. PMID: 11867540 Free PMC article.
hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells.
Taipale M, Rea S, Richter K, Vilar A, Lichter P, Imhof A, Akhtar A. Taipale M, et al. Among authors: rea s. Mol Cell Biol. 2005 Aug;25(15):6798-810. doi: 10.1128/MCB.25.15.6798-6810.2005. Mol Cell Biol. 2005. PMID: 16024812 Free PMC article.
Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
Kubicek S, O'Sullivan RJ, August EM, Hickey ER, Zhang Q, Teodoro ML, Rea S, Mechtler K, Kowalski JA, Homon CA, Kelly TA, Jenuwein T. Kubicek S, et al. Among authors: rea s. Mol Cell. 2007 Feb 9;25(3):473-81. doi: 10.1016/j.molcel.2007.01.017. Mol Cell. 2007. PMID: 17289593
Of those, one inhibitor, BIX-01294 (diazepin-quinazolin-amine derivative), does not compete with the cofactor S-adenosyl-methionine, and selectively impairs the G9a HMTase and the generation of H3K9me2 in vitro. ...
Of those, one inhibitor, BIX-01294 (diazepin-quinazolin-amine derivative), does not compete with the cofactor S-adenosyl-methionine, …
Msl2 is a novel component of the vertebrate DNA damage response.
Lai Z, Moravcová S, Canitrot Y, Andrzejewski LP, Walshe DM, Rea S. Lai Z, et al. Among authors: rea s. PLoS One. 2013 Jul 9;8(7):e68549. doi: 10.1371/journal.pone.0068549. Print 2013. PLoS One. 2013. PMID: 23874665 Free PMC article.
Cognitive analysis of schizophrenia risk genes that function as epigenetic regulators of gene expression.
Whitton L, Cosgrove D, Clarkson C, Harold D, Kendall K, Richards A, Mantripragada K, Owen MJ, O'Donovan MC, Walters J, Hartmann A, Konte B, Rujescu D; WTCCC2, Gill M, Corvin A, Rea S, Donohoe G, Morris DW. Whitton L, et al. Among authors: rea s. Am J Med Genet B Neuropsychiatr Genet. 2016 Dec;171(8):1170-1179. doi: 10.1002/ajmg.b.32503. Epub 2016 Oct 20. Am J Med Genet B Neuropsychiatr Genet. 2016. PMID: 27762073
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