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The persistence in the liver of residual duck hepatitis B virus covalently closed circular DNA is not dependent upon new viral DNA synthesis.
Reaiche GY, Le Mire MF, Mason WS, Jilbert AR. Reaiche GY, et al. Virology. 2010 Oct 25;406(2):286-92. doi: 10.1016/j.virol.2010.07.013. Epub 2010 Aug 12. Virology. 2010. PMID: 20705309 Free article.
Antiviral therapy with entecavir combined with post-exposure "prime-boost" vaccination eliminates duck hepatitis B virus-infected hepatocytes and prevents the development of persistent infection.
Miller DS, Boyle D, Feng F, Reaiche GY, Kotlarski I, Colonno R, Jilbert AR. Miller DS, et al. Among authors: reaiche gy. Virology. 2008 Apr 10;373(2):329-41. doi: 10.1016/j.virol.2007.11.032. Epub 2008 Jan 18. Virology. 2008. PMID: 18206204 Free article.