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AID/APOBEC deaminases and cancer.
Rebhandl S, Huemer M, Greil R, Geisberger R. Rebhandl S, et al. Oncoscience. 2015 Apr 28;2(4):320-33. doi: 10.18632/oncoscience.155. eCollection 2015. Oncoscience. 2015. PMID: 26097867 Free PMC article. Review.
Imprecision and DNA Break Repair Biased towards Incompatible End Joining in Leukemia.
Gassner FJ, Schubert M, Rebhandl S, Spandl K, Zaborsky N, Catakovic K, Blaimer S, Hebenstreit D, Greil R, Geisberger R. Gassner FJ, et al. Among authors: rebhandl s. Mol Cancer Res. 2018 Mar;16(3):428-438. doi: 10.1158/1541-7786.MCR-17-0373. Epub 2017 Dec 8. Mol Cancer Res. 2018. PMID: 29222170 Free PMC article.
AIDing cancer treatment: Reducing AID activity via HSP90 inhibition.
Rebhandl S, Geisberger R. Rebhandl S, et al. Eur J Immunol. 2015 Aug;45(8):2208-11. doi: 10.1002/eji.201545832. Epub 2015 Jul 7. Eur J Immunol. 2015. PMID: 26151367 Free PMC article.
Alternative splice variants of AID are not stoichiometrically present at the protein level in chronic lymphocytic leukemia.
Rebhandl S, Huemer M, Zaborsky N, Gassner FJ, Catakovic K, Felder TK, Greil R, Geisberger R. Rebhandl S, et al. Eur J Immunol. 2014 Jul;44(7):2175-87. doi: 10.1002/eji.201343853. Epub 2014 Apr 15. Eur J Immunol. 2014. PMID: 24668151 Free PMC article.
AID induces intraclonal diversity and genomic damage in CD86(+) chronic lymphocytic leukemia cells.
Huemer M, Rebhandl S, Zaborsky N, Gassner FJ, Hainzl S, Weiss L, Hebenstreit D, Greil R, Geisberger R. Huemer M, et al. Among authors: rebhandl s. Eur J Immunol. 2014 Dec;44(12):3747-57. doi: 10.1002/eji.201344421. Epub 2014 Oct 18. Eur J Immunol. 2014. PMID: 25179679 Free PMC article. Clinical Trial.
APOBEC3 signature mutations in chronic lymphocytic leukemia.
Rebhandl S, Huemer M, Gassner FJ, Zaborsky N, Hebenstreit D, Catakovic K, Grössinger EM, Greil R, Geisberger R. Rebhandl S, et al. Leukemia. 2014 Sep;28(9):1929-32. doi: 10.1038/leu.2014.160. Epub 2014 May 20. Leukemia. 2014. PMID: 24840555 Free PMC article. No abstract available.
CD1d expression on chronic lymphocytic leukemia B cells affects disease progression and induces T cell skewing in CD8 positive and CD4CD8 double negative T cells.
Zaborsky N, Gassner FJ, Asslaber D, Reinthaler P, Denk U, Flenady S, Hofbauer JP, Danner B, Rebhandl S, Harrer A, Geisberger R, Greil R, Egle A. Zaborsky N, et al. Among authors: rebhandl s. Oncotarget. 2016 Aug 2;7(31):49459-49469. doi: 10.18632/oncotarget.10372. Oncotarget. 2016. PMID: 27385215 Free PMC article.
Chemotherapy-induced augmentation of T cells expressing inhibitory receptors is reversed by treatment with lenalidomide in chronic lymphocytic leukemia.
Gassner FJ, Zaborsky N, Neureiter D, Huemer M, Melchardt T, Egle A, Rebhandl S, Catakovic K, Hartmann TN, Greil R, Geisberger R. Gassner FJ, et al. Among authors: rebhandl s. Haematologica. 2014 May;99(5):67-9. doi: 10.3324/haematol.2013.098459. Epub 2014 Feb 21. Haematologica. 2014. PMID: 24561794 Free PMC article. No abstract available.
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia.
Catakovic K, Gassner FJ, Ratswohl C, Zaborsky N, Rebhandl S, Schubert M, Steiner M, Gutjahr JC, Pleyer L, Egle A, Hartmann TN, Greil R, Geisberger R. Catakovic K, et al. Among authors: rebhandl s. Oncoimmunology. 2017 Sep 21;7(1):e1371399. doi: 10.1080/2162402X.2017.1371399. eCollection 2017. Oncoimmunology. 2017. PMID: 29296521 Free PMC article.
Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade.
Grössinger EM, Weiss L, Zierler S, Rebhandl S, Krenn PW, Hinterseer E, Schmölzer J, Asslaber D, Hainzl S, Neureiter D, Egle A, Piñón-Hofbauer J, Hartmann TN, Greil R, Kerschbaum HH. Grössinger EM, et al. Among authors: rebhandl s. Leukemia. 2014 Apr;28(4):954-8. doi: 10.1038/leu.2014.37. Epub 2014 Jan 20. Leukemia. 2014. PMID: 24441290 No abstract available.
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