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2013 1
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Recent progress in the use of zebrafish for novel cardiac drug discovery.
Keßler M, Rottbauer W, Just S. Keßler M, et al. Expert Opin Drug Discov. 2015;10(11):1231-41. doi: 10.1517/17460441.2015.1078788. Epub 2015 Aug 18. Expert Opin Drug Discov. 2015. PMID: 26294375 Review.
In this context, the zebrafish has emerged as an important in vivo vertebrate animal system to study and to model human cardiovascular diseases as well as for in vivo cardiovascular drug discovery. AREAS COVERED: This review describes the ration …
In this context, the zebrafish has emerged as an important in vivo vertebrate animal system to study and to model human cardiovasc
Recent advances in in vivo screening for antiarrhythmic drugs.
MacRae CA. MacRae CA. Expert Opin Drug Discov. 2013 Feb;8(2):131-41. doi: 10.1517/17460441.2013.743990. Epub 2013 Jan 12. Expert Opin Drug Discov. 2013. PMID: 23311759 Review.
AREAS COVERED: This review outlines the emerging biology underlying potentially lethal rhythm disturbances, and highlights the problems that these novel mechanisms present for rational target identification in the traditional framework of drug discovery. The …
AREAS COVERED: This review outlines the emerging biology underlying potentially lethal rhythm disturbances, and highlights the problems that …