Redler RL - Search Results

1

Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity.

Tsao D, Wieskopf JS, Rashid N, Sorge RE, Redler RL, Segall SK, Mogil JS, Maixner W, Dokholyan NV, Diatchenko L. Tsao D, et al. Among authors: redler rl. Mol Pain. 2012 Apr 13;8:25. doi: 10.1186/1744-8069-8-25. Mol Pain. 2012. PMID: 22500608 Free PMC article.

2

The complex molecular biology of amyotrophic lateral sclerosis (ALS).

Redler RL, Dokholyan NV. Redler RL, et al. Prog Mol Biol Transl Sci. 2012;107:215-62. doi: 10.1016/B978-0-12-385883-2.00002-3. Prog Mol Biol Transl Sci. 2012. PMID: 22482452 Free PMC article. Review.

3

Cu,Zn-superoxide dismutase without Zn is folded but catalytically inactive.

Nedd S, Redler RL, Proctor EA, Dokholyan NV, Alexandrova AN. Nedd S, et al. Among authors: redler rl. J Mol Biol. 2014 Dec 12;426(24):4112-4124. doi: 10.1016/j.jmb.2014.07.016. Epub 2014 Jul 30. J Mol Biol. 2014. PMID: 25083917 Free PMC article.

4

Protein Destabilization as a Common Factor in Diverse Inherited Disorders.

Redler RL, Das J, Diaz JR, Dokholyan NV. Redler RL, et al. J Mol Evol. 2016 Jan;82(1):11-6. doi: 10.1007/s00239-015-9717-5. Epub 2015 Nov 19. J Mol Evol. 2016. PMID: 26584803 Free PMC article.

5

Computational approaches to understanding protein aggregation in neurodegeneration.

Redler RL, Shirvanyants D, Dagliyan O, Ding F, Kim DN, Kota P, Proctor EA, Ramachandran S, Tandon A, Dokholyan NV. Redler RL, et al. J Mol Cell Biol. 2014 Apr;6(2):104-15. doi: 10.1093/jmcb/mju007. Epub 2014 Mar 11. J Mol Cell Biol. 2014. PMID: 24620031 Free PMC article. Review.

6

Glutathionylation at Cys-111 induces dissociation of wild type and FALS mutant SOD1 dimers.

Redler RL, Wilcox KC, Proctor EA, Fee L, Caplow M, Dokholyan NV. Redler RL, et al. Biochemistry. 2011 Aug 16;50(32):7057-66. doi: 10.1021/bi200614y. Epub 2011 Jul 18. Biochemistry. 2011. PMID: 21739997 Free PMC article.

7

Non-native soluble oligomers of Cu/Zn superoxide dismutase (SOD1) contain a conformational epitope linked to cytotoxicity in amyotrophic lateral sclerosis (ALS).

Redler RL, Fee L, Fay JM, Caplow M, Dokholyan NV. Redler RL, et al. Biochemistry. 2014 Apr 15;53(14):2423-32. doi: 10.1021/bi500158w. Epub 2014 Apr 2. Biochemistry. 2014. PMID: 24660965 Free PMC article.

8

Modifications of superoxide dismutase (SOD1) in human erythrocytes: a possible role in amyotrophic lateral sclerosis.

Wilcox KC, Zhou L, Jordon JK, Huang Y, Yu Y, Redler RL, Chen X, Caplow M, Dokholyan NV. Wilcox KC, et al. Among authors: redler rl. J Biol Chem. 2009 May 15;284(20):13940-13947. doi: 10.1074/jbc.M809687200. Epub 2009 Mar 19. J Biol Chem. 2009. PMID: 19299510 Free PMC article.

9

Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis.

Proctor EA, Fee L, Tao Y, Redler RL, Fay JM, Zhang Y, Lv Z, Mercer IP, Deshmukh M, Lyubchenko YL, Dokholyan NV. Proctor EA, et al. Among authors: redler rl. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):614-9. doi: 10.1073/pnas.1516725113. Epub 2015 Dec 30. Proc Natl Acad Sci U S A. 2016. PMID: 26719414 Free PMC article.

10

Design of multi-scale protein complexes by hierarchical building block fusion.

Hsia Y, Mout R, Sheffler W, Edman NI, Vulovic I, Park YJ, Redler RL, Bick MJ, Bera AK, Courbet A, Kang A, Brunette TJ, Nattermann U, Tsai E, Saleem A, Chow CM, Ekiert D, Bhabha G, Veesler D, Baker D. Hsia Y, et al. Among authors: redler rl. Nat Commun. 2021 Apr 16;12(1):2294. doi: 10.1038/s41467-021-22276-z. Nat Commun. 2021. PMID: 33863889 Free PMC article.

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