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Acid-labile subunit (ALS) deficiency.
Best Pract Res Clin Endocrinol Metab. 2011 Feb;25(1):101-13. doi: 10.1016/j.beem.2010.08.010.
Best Pract Res Clin Endocrinol Metab. 2011.
PMID: 21396577
Review.
The acid-labile subunit (ALS) protein is crucial for maintaining the integrity of the circulating IGF/IGFBP system. In humans, complete ALS deficiency is characterized by severely reduced serum IGF-I and IGFBP-3 concentrations that is inc …
The acid-labile subunit (ALS) protein is crucial for maintaining the integrity of the circulating IGF/IGFBP syst …
Acid-labile subunit deficiency: phenotypic similarities and differences between human and mouse.
Domené HM, Bengolea SV, Jasper HG, Boisclair YR.
Domené HM, et al.
J Endocrinol Invest. 2005;28(5 Suppl):43-6.
J Endocrinol Invest. 2005.
PMID: 16114275
Review.
IGF-I and IGF-II (IGFs) form higher molecular weight complexes with specific binding proteins (IGFBP-1 to -6). These complexes are referred to as binary complexes consisting of IGF-I or IGF-II and one IGFBP, or as ternary complexes each consisting of either of IGF-I or IGF …
IGF-I and IGF-II (IGFs) form higher molecular weight complexes with specific binding proteins (IGFBP-1 to -6). These complexes are re …
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