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Reduction in recombinant human erythropoietin doses by the use of chronic intravenous iron supplementation.
Fishbane S, Frei GL, Maesaka J. Fishbane S, et al. Am J Kidney Dis. 1995 Jul;26(1):41-6. doi: 10.1016/0272-6386(95)90151-5. Am J Kidney Dis. 1995. PMID: 7611266 Free article. Clinical Trial.
We have found that administering iron intravenously instead of orally for chronic maintenance iron supplementation in hemodialysis patients resulted in improved erythropoiesis. We hypothesize that most hemodialysis patients have inadequate ir …
We have found that administering iron intravenously instead of orally for chronic maintenance iron supplement …
Reduction in erythropoietin doses by the use of chronic intravenous iron supplementation in iron-replete hemodialysis patients.
Chang CH, Chang CC, Chiang SS. Chang CH, et al. Clin Nephrol. 2002 Feb;57(2):136-41. doi: 10.5414/cnp57136. Clin Nephrol. 2002. PMID: 11863124 Clinical Trial.
BACKGROUND: Iron deficiency is the most common cause of suboptimal response to recombinant human erythropoietin (rHuEPO) in chronic hemodialysis (HD) patients. ...METHODS: We conducted a 12-month intravenous iron substitution trial …
BACKGROUND: Iron deficiency is the most common cause of suboptimal response to recombinant human erythropoietin …
Safety aspects of parenteral iron in patients with end-stage renal disease.
Sunder-Plassmann G, Hörl WH. Sunder-Plassmann G, et al. Drug Saf. 1997 Oct;17(4):241-50. doi: 10.2165/00002018-199717040-00004. Drug Saf. 1997. PMID: 9352960 Review.
Absolute and functional iron deficiency is the most common cause of epoetin (recombinant human erythropoietin) hyporesponsiveness in renal failure patients. ...Patients with iron deficiency should receive supplemental iron, …
Absolute and functional iron deficiency is the most common cause of epoetin (recombinant human erythropoietin …
Recombinant human erythropoietin: 10 years of clinical experience.
Winearls CG. Winearls CG. Nephrol Dial Transplant. 1998;13 Suppl 2:3-8. doi: 10.1093/ndt/13.suppl_2.3. Nephrol Dial Transplant. 1998. PMID: 9566483 Review.
The need for a renewable source of erythropoietin to treat the anaemia of chronic renal failure was first recognized in the 1960s, but cloning and expression of the human gene was not achieved until 1983. Clinical testing of recombinant human …
The need for a renewable source of erythropoietin to treat the anaemia of chronic renal failure was first recognized in the 19 …
Effect of an intravenous iron dextran regimen on iron stores, hemoglobin, and erythropoietin requirements in hemodialysis patients.
Park L, Uhthoff T, Tierney M, Nadler S. Park L, et al. Am J Kidney Dis. 1998 May;31(5):835-40. doi: 10.1016/s0272-6386(98)70053-8. Am J Kidney Dis. 1998. PMID: 9590194
Although oral iron is often prescribed to replete iron stores, this approach to iron supplementation may not be adequate with chronic EPO therapy. Intravenous (IV) iron dextran may be an effective alternative approach to replete …
Although oral iron is often prescribed to replete iron stores, this approach to iron supplementation may not be …
Economic appraisal of maintenance parenteral iron administration in treatment of anaemia in chronic haemodialysis patients.
Sepandj F, Jindal K, West M, Hirsch D. Sepandj F, et al. Nephrol Dial Transplant. 1996 Feb;11(2):319-22. doi: 10.1093/oxfordjournals.ndt.a027260. Nephrol Dial Transplant. 1996. PMID: 8671786
Intermittent doses of intravenous iron dextran complex are recommended in patients with inadequate iron stores despite maximal tolerated oral dose. ...A carefully monitored regimen of maintenance parenteral iron is a safe, effective, and economi …
Intermittent doses of intravenous iron dextran complex are recommended in patients with inadequate iron stores d …
Epoetin alfa: basic biology and clinical utility in cancer patients.
Littlewood T, Collins G. Littlewood T, et al. Expert Rev Anticancer Ther. 2005 Dec;5(6):947-56. doi: 10.1586/14737140.5.6.947. Expert Rev Anticancer Ther. 2005. PMID: 16336085 Review.
In myeloid disorders such as myelodysplasia, response to single-agent recombinant human erythropoietin is disappointing but significant synergism with granulocyte colony stimulating factor has been demonstrated and different dosing regimens may also im …
In myeloid disorders such as myelodysplasia, response to single-agent recombinant human erythropoietin is disappointing …
The evaluation of postdialysis L-carnitine administration and its effect on weekly requiring doses of rHuEPO in hemodialysis patients.
Kadiroglu AK, Yilmaz ME, Sit D, Kara IH, Isikoglu B. Kadiroglu AK, et al. Ren Fail. 2005;27(4):367-72. Ren Fail. 2005. PMID: 16060121
BACKGROUND: In this study, our aim was to evaluate the effect of postdialysis administration of parenteral L-carnitine supplementations on hematological parameters and also on weekly requiring dose of the recombinant human erythropoietine (rHuEPO) in hemodial …
BACKGROUND: In this study, our aim was to evaluate the effect of postdialysis administration of parenteral L-carnitine supplementations …