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Caspase-9 can be activated without proteolytic processing.
Stennicke HR, Deveraux QL, Humke EW, Reed JC, Dixit VM, Salvesen GS. Stennicke HR, et al. Among authors: reed jc. J Biol Chem. 1999 Mar 26;274(13):8359-62. doi: 10.1074/jbc.274.13.8359. J Biol Chem. 1999. PMID: 10085063 Free article.
A single BIR domain of XIAP sufficient for inhibiting caspases.
Takahashi R, Deveraux Q, Tamm I, Welsh K, Assa-Munt N, Salvesen GS, Reed JC. Takahashi R, et al. Among authors: reed jc. J Biol Chem. 1998 Apr 3;273(14):7787-90. doi: 10.1074/jbc.273.14.7787. J Biol Chem. 1998. PMID: 9525868 Free article.
Pro-caspase-3 is a major physiologic target of caspase-8.
Stennicke HR, Jürgensmeier JM, Shin H, Deveraux Q, Wolf BB, Yang X, Zhou Q, Ellerby HM, Ellerby LM, Bredesen D, Green DR, Reed JC, Froelich CJ, Salvesen GS. Stennicke HR, et al. Among authors: reed jc. J Biol Chem. 1998 Oct 16;273(42):27084-90. doi: 10.1074/jbc.273.42.27084. J Biol Chem. 1998. PMID: 9765224 Free article.
Regulation of cell death protease caspase-9 by phosphorylation.
Cardone MH, Roy N, Stennicke HR, Salvesen GS, Franke TF, Stanbridge E, Frisch S, Reed JC. Cardone MH, et al. Among authors: reed jc. Science. 1998 Nov 13;282(5392):1318-21. doi: 10.1126/science.282.5392.1318. Science. 1998. PMID: 9812896
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia.
Krajewski S, Krajewska M, Ellerby LM, Welsh K, Xie Z, Deveraux QL, Salvesen GS, Bredesen DE, Rosenthal RE, Fiskum G, Reed JC. Krajewski S, et al. Among authors: reed jc. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5752-7. doi: 10.1073/pnas.96.10.5752. Proc Natl Acad Sci U S A. 1999. PMID: 10318956 Free PMC article.
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