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Intravenous immunoglobulin for repeated IVF failure and unexplained infertility.
Virro MR, Winger EE, Reed JL. Virro MR, et al. Am J Reprod Immunol. 2012 Sep;68(3):218-25. doi: 10.1111/j.1600-0897.2012.01169.x. Epub 2012 Jul 17. Am J Reprod Immunol. 2012. PMID: 22805355
Die-off ratio correlates with increased TNF-α:IL-10 ratio and decreased IVF success rates correctable with humira.
Winger EE, Reed JL, Ashoush S, El-Toukhy T, Taranissi M. Winger EE, et al. Am J Reprod Immunol. 2012 Nov;68(5):428-37. doi: 10.1111/j.1600-0897.2012.01179.x. Epub 2012 Jul 30. Am J Reprod Immunol. 2012. PMID: 22845061
Elevated preconception CD56+ 16+ and/or Th1:Th2 levels predict benefit from IVIG therapy in subfertile women undergoing IVF.
Winger EE, Reed JL, Ashoush S, El-Toukhy T, Ahuja S, Taranissi M. Winger EE, et al. Am J Reprod Immunol. 2011 Nov;66(5):394-403. doi: 10.1111/j.1600-0897.2011.01018.x. Epub 2011 May 30. Am J Reprod Immunol. 2011. PMID: 21623994
Birth defect rates in women using Adalimumab (Humira(®) ) to treat immunologic-based infertility in IVF patients.
Winger EE, Reed JL, Ashoush S, El-Toukhy T, Ahuja S, Taranissi M. Winger EE, et al. Am J Reprod Immunol. 2011 Sep;66(3):237-41. doi: 10.1111/j.1600-0897.2011.00994.x. Epub 2011 Apr 19. Am J Reprod Immunol. 2011. PMID: 21501282
Degree of TNF-α/IL-10 cytokine elevation correlates with IVF success rates in women undergoing treatment with Adalimumab (Humira) and IVIG.
Winger EE, Reed JL, Ashoush S, El-Toukhy T, Ahuja S, Taranissi M. Winger EE, et al. Am J Reprod Immunol. 2011 Jun;65(6):610-8. doi: 10.1111/j.1600-0897.2010.00946.x. Epub 2011 Jan 12. Am J Reprod Immunol. 2011. PMID: 21223418
Treatment with tumor necrosis factor inhibitors and intravenous immunoglobulin improves live birth rates in women with recurrent spontaneous abortion.
Winger EE, Reed JL. Winger EE, et al. Am J Reprod Immunol. 2008 Jul;60(1):8-16. doi: 10.1111/j.1600-0897.2008.00585.x. Epub 2008 Apr 1. Am J Reprod Immunol. 2008. PMID: 18422811
Treatment with adalimumab (Humira) and intravenous immunoglobulin improves pregnancy rates in women undergoing IVF.
Winger EE, Reed JL, Ashoush S, Ahuja S, El-Toukhy T, Taranissi M. Winger EE, et al. Am J Reprod Immunol. 2009 Feb;61(2):113-20. doi: 10.1111/j.1600-0897.2008.00669.x. Epub 2008 Dec 3. Am J Reprod Immunol. 2009. PMID: 19055656
First trimester PBMC microRNA predicts adverse pregnancy outcome.
Winger EE, Reed JL, Ji X. Winger EE, et al. Am J Reprod Immunol. 2014 Nov;72(5):515-26. doi: 10.1111/aji.12287. Epub 2014 Jun 28. Am J Reprod Immunol. 2014. PMID: 24974972
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