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The design of metal-binding sites in proteins.
Regan L. Regan L. Annu Rev Biophys Biomol Struct. 1993;22:257-87. doi: 10.1146/annurev.bb.22.060193.001353. Annu Rev Biophys Biomol Struct. 1993. PMID: 8347991 Review. No abstract available.
Protein design: novel metal-binding sites.
Regan L. Regan L. Trends Biochem Sci. 1995 Jul;20(7):280-5. doi: 10.1016/s0968-0004(00)89044-1. Trends Biochem Sci. 1995. PMID: 7667881 Free article. Review.
Novel metal-binding proteins by design.
Klemba M, Gardner KH, Marino S, Clarke ND, Regan L. Klemba M, et al. Among authors: regan l. Nat Struct Biol. 1995 May;2(5):368-73. doi: 10.1038/nsb0595-368. Nat Struct Biol. 1995. PMID: 7664093
Protein design.
Regan L. Regan L. Curr Opin Biotechnol. 1991 Aug;2(4):544-50. doi: 10.1016/0958-1669(91)90079-k. Curr Opin Biotechnol. 1991. PMID: 1367674 Review.
Proteins to order?
Regan L. Regan L. Structure. 1998 Jan 15;6(1):1-4. doi: 10.1016/s0969-2126(98)00001-x. Structure. 1998. PMID: 9493261 Free article. Review. No abstract available.
Characterization of metal binding by a designed protein: single ligand substitutions at a tetrahedral Cys2His2 site.
Klemba M, Regan L. Klemba M, et al. Among authors: regan l. Biochemistry. 1995 Aug 8;34(31):10094-100. doi: 10.1021/bi00031a034. Biochemistry. 1995. PMID: 7632681
The tetrahedral Cys2His2 Zn(II)-binding site in the de novo designed protein Z alpha 4 [Regan, L., & Clarke, N. D. (1990) Biochemistry 29, 10878] has been studied by independently mutating each of the metal-binding ligands to alanine. ...
The tetrahedral Cys2His2 Zn(II)-binding site in the de novo designed protein Z alpha 4 [Regan, L., & Clarke, N. D. (1990) …
Ligand binding by repeat proteins: natural and designed.
Grove TZ, Cortajarena AL, Regan L. Grove TZ, et al. Among authors: regan l. Curr Opin Struct Biol. 2008 Aug;18(4):507-15. doi: 10.1016/j.sbi.2008.05.008. Epub 2008 Jul 23. Curr Opin Struct Biol. 2008. PMID: 18602006 Free PMC article. Review.
Sequence variation in ligand binding sites in proteins.
Magliery TJ, Regan L. Magliery TJ, et al. Among authors: regan l. BMC Bioinformatics. 2005 Sep 30;6:240. doi: 10.1186/1471-2105-6-240. BMC Bioinformatics. 2005. PMID: 16194281 Free PMC article.
A new folding paradigm for repeat proteins.
Kajander T, Cortajarena AL, Main ER, Mochrie SG, Regan L. Kajander T, et al. Among authors: regan l. J Am Chem Soc. 2005 Jul 27;127(29):10188-90. doi: 10.1021/ja0524494. J Am Chem Soc. 2005. PMID: 16028928
535 results